Genetic Analysis of Multiple Primary Malignant Tumors in Women with Breast and Ovarian Cancer

Familial cancer syndromes, which are commonly caused by germline mutations in oncogenes and tumor suppressor genes, are generally considered to be the cause of primary multiple malignant neoplasias (PMMNs). Using targeted genomic sequencing, we screened for eight germline mutations: <i>BRCA1&l...

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Bibliographic Details
Main Authors: Alina Savkova, Lyudmila Gulyaeva, Aleksey Gerasimov, Sergey Krasil’nikov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/7/6705