Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy

Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy

Abstract Immunotherapy for cancer is a rapidly developing treatment that modifies the immune system and enhances the antitumor immune response. B7-H3 (CD276), a member of the B7 family that plays an immunoregulatory role in the T cell response, has been highlighted as a novel potential target for ca...

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Bibliographic Details
Main Authors: Binghao Zhao, Huanzhang Li, Yu Xia, Yaning Wang, Yuekun Wang, Yixin Shi, Hao Xing, Tian Qu, Yu Wang, Wenbin Ma
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Hematology & Oncology
Subjects:
B7-H3
Tumor microenvironment
Cancer immune checkpoints
Cancer immunotherapy
Biomarker
Online Access:https://doi.org/10.1186/s13045-022-01364-7

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