Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
<p>Abstract</p> <p>Background</p> <p>Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such as transmembrane protein topology prediction, the incorporation o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-04-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://www.biomedcentral.com/1471-2105/7/189 |