ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
In this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significan...
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Format: | Article |
Language: | English |
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Editura Universităţii din Oradea
2016-05-01
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Series: | Annals of the University of Oradea: Fascicle of Textiles, Leatherwork |
Subjects: | |
Online Access: | http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdf |
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author | DJORDJEVIC Dragan AMIN Goran MICIC Aleksandra MILIC Dragan SMELCEROVIC Miodrag |
author_facet | DJORDJEVIC Dragan AMIN Goran MICIC Aleksandra MILIC Dragan SMELCEROVIC Miodrag |
author_sort | DJORDJEVIC Dragan |
collection | DOAJ |
description | In this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significantly improved performance. All compounds were characterized and evaluated for their anti-microbial activity against 7 pathogenic bacteria, 1 parasitic protozoan and 1 fungus. It estimated anti-bacterial activity in vitro against the following microorganisms Staphylococcus aureus, Bacillus anthracis, Streptococcus faecalis, Enterobacter sp., Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, and Candida albicans. The anti-amoebic activity in vitro was evaluated against the HM1: IMSS strain of Entamoeba histolytica and the results were compared with the standard drug, metronidazole. The synthesized azomethines, showed very good substantivity for wool fibers, gave fine coloring, with good degree of exhaustion after dyeing. The combination of extended synthetic analogues of natural molecules leads to discovery of chemical entities which might be excellent anti-microbial and anti-amoebic compounds as depicted in our results. Being highly the effects this compound can be explored in future as an option for decreasing pathogenic potential of infecting from different sources. Azomethines containing hydrazone (dyestuff 1) and phenylhydrazone (dyestuff 2) as moiety show average yield and moderate inhibition activity while azomethines containing thiosemicarbazone (dyestuff 3) as moiety show higher yield and greater inhibition activity towards gram-negative and gram-positive bacteria as well as a fungus. |
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format | Article |
id | doaj.art-70bd541dfcd341fd8798f8d8f5a0e74a |
institution | Directory Open Access Journal |
issn | 1843-813X |
language | English |
last_indexed | 2024-12-21T06:49:44Z |
publishDate | 2016-05-01 |
publisher | Editura Universităţii din Oradea |
record_format | Article |
series | Annals of the University of Oradea: Fascicle of Textiles, Leatherwork |
spelling | doaj.art-70bd541dfcd341fd8798f8d8f5a0e74a2022-12-21T19:12:30ZengEditura Universităţii din OradeaAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork1843-813X2016-05-01XVII24146ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFSDJORDJEVIC Dragan0AMIN Goran1MICIC Aleksandra2MILIC Dragan3SMELCEROVIC Miodrag4University of Nis, Faculty of Technology, Textile Department, Bulevar oslobodjenja 124, 16000 Leskovac, SerbiaUniversity of Nis, Faculty of Technology, Textile Department, Bulevar oslobodjenja 124, 16000 Leskovac, SerbiaHigher Vocational School for Textile, Textile Department, Vilema Pusmana 17, 16000 Leskovac, SerbiaCenter of the Ministry of Defence Leskovac, Majora Tepica 4, 16000 Leskovac, SerbiaHigher Vocational School for Textile, Textile Department, Vilema Pusmana 17, 16000 Leskovac, SerbiaIn this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significantly improved performance. All compounds were characterized and evaluated for their anti-microbial activity against 7 pathogenic bacteria, 1 parasitic protozoan and 1 fungus. It estimated anti-bacterial activity in vitro against the following microorganisms Staphylococcus aureus, Bacillus anthracis, Streptococcus faecalis, Enterobacter sp., Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, and Candida albicans. The anti-amoebic activity in vitro was evaluated against the HM1: IMSS strain of Entamoeba histolytica and the results were compared with the standard drug, metronidazole. The synthesized azomethines, showed very good substantivity for wool fibers, gave fine coloring, with good degree of exhaustion after dyeing. The combination of extended synthetic analogues of natural molecules leads to discovery of chemical entities which might be excellent anti-microbial and anti-amoebic compounds as depicted in our results. Being highly the effects this compound can be explored in future as an option for decreasing pathogenic potential of infecting from different sources. Azomethines containing hydrazone (dyestuff 1) and phenylhydrazone (dyestuff 2) as moiety show average yield and moderate inhibition activity while azomethines containing thiosemicarbazone (dyestuff 3) as moiety show higher yield and greater inhibition activity towards gram-negative and gram-positive bacteria as well as a fungus.http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdfAzomethineAnti-bacterialAnti-amoebicDyeingWool |
spellingShingle | DJORDJEVIC Dragan AMIN Goran MICIC Aleksandra MILIC Dragan SMELCEROVIC Miodrag ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS Annals of the University of Oradea: Fascicle of Textiles, Leatherwork Azomethine Anti-bacterial Anti-amoebic Dyeing Wool |
title | ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS |
title_full | ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS |
title_fullStr | ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS |
title_full_unstemmed | ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS |
title_short | ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS |
title_sort | anti microbial and anti amoebic activity some azomethines potential textile dyestuffs |
topic | Azomethine Anti-bacterial Anti-amoebic Dyeing Wool |
url | http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdf |
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