ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS

In this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significan...

Full description

Bibliographic Details
Main Authors: DJORDJEVIC Dragan, AMIN Goran, MICIC Aleksandra, MILIC Dragan, SMELCEROVIC Miodrag
Format: Article
Language:English
Published: Editura Universităţii din Oradea 2016-05-01
Series:Annals of the University of Oradea: Fascicle of Textiles, Leatherwork
Subjects:
Online Access:http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdf
_version_ 1819031670429319168
author DJORDJEVIC Dragan
AMIN Goran
MICIC Aleksandra
MILIC Dragan
SMELCEROVIC Miodrag
author_facet DJORDJEVIC Dragan
AMIN Goran
MICIC Aleksandra
MILIC Dragan
SMELCEROVIC Miodrag
author_sort DJORDJEVIC Dragan
collection DOAJ
description In this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significantly improved performance. All compounds were characterized and evaluated for their anti-microbial activity against 7 pathogenic bacteria, 1 parasitic protozoan and 1 fungus. It estimated anti-bacterial activity in vitro against the following microorganisms Staphylococcus aureus, Bacillus anthracis, Streptococcus faecalis, Enterobacter sp., Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, and Candida albicans. The anti-amoebic activity in vitro was evaluated against the HM1: IMSS strain of Entamoeba histolytica and the results were compared with the standard drug, metronidazole. The synthesized azomethines, showed very good substantivity for wool fibers, gave fine coloring, with good degree of exhaustion after dyeing. The combination of extended synthetic analogues of natural molecules leads to discovery of chemical entities which might be excellent anti-microbial and anti-amoebic compounds as depicted in our results. Being highly the effects this compound can be explored in future as an option for decreasing pathogenic potential of infecting from different sources. Azomethines containing hydrazone (dyestuff 1) and phenylhydrazone (dyestuff 2) as moiety show average yield and moderate inhibition activity while azomethines containing thiosemicarbazone (dyestuff 3) as moiety show higher yield and greater inhibition activity towards gram-negative and gram-positive bacteria as well as a fungus.
first_indexed 2024-12-21T06:49:44Z
format Article
id doaj.art-70bd541dfcd341fd8798f8d8f5a0e74a
institution Directory Open Access Journal
issn 1843-813X
language English
last_indexed 2024-12-21T06:49:44Z
publishDate 2016-05-01
publisher Editura Universităţii din Oradea
record_format Article
series Annals of the University of Oradea: Fascicle of Textiles, Leatherwork
spelling doaj.art-70bd541dfcd341fd8798f8d8f5a0e74a2022-12-21T19:12:30ZengEditura Universităţii din OradeaAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork1843-813X2016-05-01XVII24146ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFSDJORDJEVIC Dragan0AMIN Goran1MICIC Aleksandra2MILIC Dragan3SMELCEROVIC Miodrag4University of Nis, Faculty of Technology, Textile Department, Bulevar oslobodjenja 124, 16000 Leskovac, SerbiaUniversity of Nis, Faculty of Technology, Textile Department, Bulevar oslobodjenja 124, 16000 Leskovac, SerbiaHigher Vocational School for Textile, Textile Department, Vilema Pusmana 17, 16000 Leskovac, SerbiaCenter of the Ministry of Defence Leskovac, Majora Tepica 4, 16000 Leskovac, SerbiaHigher Vocational School for Textile, Textile Department, Vilema Pusmana 17, 16000 Leskovac, SerbiaIn this paper, new synthesized three azomethine derivatives applied in dyeing textiles checking the anti-microbial properties of active components, at the same time [1-3]. The emphasis is thrown on the verification of anti-microbial properties that are important for obtaining textile with significantly improved performance. All compounds were characterized and evaluated for their anti-microbial activity against 7 pathogenic bacteria, 1 parasitic protozoan and 1 fungus. It estimated anti-bacterial activity in vitro against the following microorganisms Staphylococcus aureus, Bacillus anthracis, Streptococcus faecalis, Enterobacter sp., Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, and Candida albicans. The anti-amoebic activity in vitro was evaluated against the HM1: IMSS strain of Entamoeba histolytica and the results were compared with the standard drug, metronidazole. The synthesized azomethines, showed very good substantivity for wool fibers, gave fine coloring, with good degree of exhaustion after dyeing. The combination of extended synthetic analogues of natural molecules leads to discovery of chemical entities which might be excellent anti-microbial and anti-amoebic compounds as depicted in our results. Being highly the effects this compound can be explored in future as an option for decreasing pathogenic potential of infecting from different sources. Azomethines containing hydrazone (dyestuff 1) and phenylhydrazone (dyestuff 2) as moiety show average yield and moderate inhibition activity while azomethines containing thiosemicarbazone (dyestuff 3) as moiety show higher yield and greater inhibition activity towards gram-negative and gram-positive bacteria as well as a fungus.http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdfAzomethineAnti-bacterialAnti-amoebicDyeingWool
spellingShingle DJORDJEVIC Dragan
AMIN Goran
MICIC Aleksandra
MILIC Dragan
SMELCEROVIC Miodrag
ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
Annals of the University of Oradea: Fascicle of Textiles, Leatherwork
Azomethine
Anti-bacterial
Anti-amoebic
Dyeing
Wool
title ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
title_full ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
title_fullStr ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
title_full_unstemmed ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
title_short ANTI-MICROBIAL AND ANTI-AMOEBIC ACTIVITY SOME AZOMETHINES - POTENTIAL TEXTILE DYESTUFFS
title_sort anti microbial and anti amoebic activity some azomethines potential textile dyestuffs
topic Azomethine
Anti-bacterial
Anti-amoebic
Dyeing
Wool
url http://textile.webhost.uoradea.ro/Annals/Vol%20XVII-No%202-2016/Textile/Art.nr.175-pag.%2041-46.pdf
work_keys_str_mv AT djordjevicdragan antimicrobialandantiamoebicactivitysomeazomethinespotentialtextiledyestuffs
AT amingoran antimicrobialandantiamoebicactivitysomeazomethinespotentialtextiledyestuffs
AT micicaleksandra antimicrobialandantiamoebicactivitysomeazomethinespotentialtextiledyestuffs
AT milicdragan antimicrobialandantiamoebicactivitysomeazomethinespotentialtextiledyestuffs
AT smelcerovicmiodrag antimicrobialandantiamoebicactivitysomeazomethinespotentialtextiledyestuffs