Role of the major histocompatibility complex class II protein presentation pathway in bone immunity imbalance in postmenopausal osteoporosis

Role of the major histocompatibility complex class II protein presentation pathway in bone immunity imbalance in postmenopausal osteoporosis

Bone immunity regulates osteoclast differentiation and bone resorption and is a potential target for the treatment of postmenopausal osteoporosis (PMOP). The molecular network between bone metabolism and the immune system is complex. However, the molecular mechanism underlying the involvement of the...

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Bibliographic Details
Main Authors: Xiaoning Wang, Xin Zhang, Yidan Han, Xinwei Duan, Jianchang Wang, Hui Yan, Shanshan Wang, Yunteng Xu, Zaishi Zhu, Lili Wang, Yanfeng Huang, Qing Lin, Xue Tan, Junkuan Zhuo, Haifeng Zhang, Min Mao, Weiying Gou, Zhouping Yi, Xihai Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Endocrinology
Subjects:
postmenopausal osteoporosis
MHC-II molecule
protein presentation pathway
effector T cells
bone immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.876067/full

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