Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum

Abstract Background Rapid diagnostic tests (RDTs) that detect histidine-rich protein 2 (PfHRP2) are used throughout Africa for the diagnosis of Plasmodium falciparum malaria. However, recent reports indicate that parasites lacking the pfhrp2 and/or histidine-rich protein 3 (pfhrp3) genes, which prod...

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Bibliographic Details
Main Authors: Jonathan B. Parr, Olivia Anderson, Jonathan J. Juliano, Steven R. Meshnick
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Malaria Journal
Subjects:
Rapid diagnostic tests
False-negative
Diagnostic resistance
Histidine-rich protein
hrp2
hrp3
Online Access:http://link.springer.com/article/10.1186/s12936-018-2287-4

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