Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Abstract Background Multiplexing of samples in single-cell RNA-seq studies allows a significant reduction of the experimental costs, straightforward identification of doublets, increased cell throughput, and reduction of sample-specific batch effects. Recently published multiplexing techniques using...

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Bibliographic Details
Main Authors: Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van den Hoecke, Isabelle Scheyltjens, Kiavash Movahedi, Hans Wils, Joke Reumers, Jeroen Van Houdt, Stein Aerts, Yvan Saeys
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Genome Biology
Subjects:
Hashing
scRNA-seq
MULTI-seq
CITE-seq
Sample multiplexing
Online Access:https://doi.org/10.1186/s13059-022-02628-8

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