Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery
The cornea is the main refractive medium of the human eye, and its clarity is critical to visual acuity. Corneal optical density (COD) is an important index to describe corneal transparency. Intact corneal epithelial and endothelial cells, regular arrangement of collagen fibers in the stroma, and no...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144455/full |
| _version_ | 1797851372439207936 |
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| author | Ye He Bo-Sheng Ma Jun-Hao Zeng Dai-Jin Ma |
| author_facet | Ye He Bo-Sheng Ma Jun-Hao Zeng Dai-Jin Ma |
| author_sort | Ye He |
| collection | DOAJ |
| description | The cornea is the main refractive medium of the human eye, and its clarity is critical to visual acuity. Corneal optical density (COD) is an important index to describe corneal transparency. Intact corneal epithelial and endothelial cells, regular arrangement of collagen fibers in the stroma, and normal substance metabolism are all integral for the cornea to maintain its transparency. In the last two decades, the Pentacam Scheimpflug imaging system has emerged as a breakthrough for the measurement of COD (also called corneal densitometry). It has been found that a wide variety of factors such as age, refractive status, and corneal diseases can affect COD. Different corneal refractive surgery methods also change COD in different corneal regions and layers and affect visual acuity following the surgery. Thus, COD has gradually become a significant indicator to evaluate corneal health, one on which the attention of clinicians has been increasingly focused. |
| first_indexed | 2024-04-09T19:15:43Z |
| format | Article |
| id | doaj.art-70ce756d952641feaa1418148238970c |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-09T19:15:43Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-70ce756d952641feaa1418148238970c2023-04-06T05:40:29ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-04-011110.3389/fbioe.2023.11444551144455Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgeryYe He0Bo-Sheng Ma1Jun-Hao Zeng2Dai-Jin Ma3Changsha Aier Eye Hospital, Changsha, ChinaDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, ChinaXiangya School of Medicine, Central South University, Changsha, ChinaChangsha Aier Eye Hospital, Changsha, ChinaThe cornea is the main refractive medium of the human eye, and its clarity is critical to visual acuity. Corneal optical density (COD) is an important index to describe corneal transparency. Intact corneal epithelial and endothelial cells, regular arrangement of collagen fibers in the stroma, and normal substance metabolism are all integral for the cornea to maintain its transparency. In the last two decades, the Pentacam Scheimpflug imaging system has emerged as a breakthrough for the measurement of COD (also called corneal densitometry). It has been found that a wide variety of factors such as age, refractive status, and corneal diseases can affect COD. Different corneal refractive surgery methods also change COD in different corneal regions and layers and affect visual acuity following the surgery. Thus, COD has gradually become a significant indicator to evaluate corneal health, one on which the attention of clinicians has been increasingly focused.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144455/fullcorneal optical densitycorneal densitometrypentacam scheimpflug imaging systemFS-LASIKSMILE |
| spellingShingle | Ye He Bo-Sheng Ma Jun-Hao Zeng Dai-Jin Ma Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery Frontiers in Bioengineering and Biotechnology corneal optical density corneal densitometry pentacam scheimpflug imaging system FS-LASIK SMILE |
| title | Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery |
| title_full | Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery |
| title_fullStr | Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery |
| title_full_unstemmed | Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery |
| title_short | Corneal optical density: Structural basis, measurements, influencing factors, and roles in refractive surgery |
| title_sort | corneal optical density structural basis measurements influencing factors and roles in refractive surgery |
| topic | corneal optical density corneal densitometry pentacam scheimpflug imaging system FS-LASIK SMILE |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144455/full |
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