Laser keratomileusis in treatment of anisometropic amblyopia in adults

PURPOSE: To compare and evaluate improvement in corrected distant visual acuity (CDVA) between myopia and hyperopia after laser in situ keratomileusis (LASIK) in adult patients with anisometropic amblyopia. MATERIALS AND METHODS: This prospective clinical study included 103 amblyopic eyes (103 patie...

Full description

Bibliographic Details
Main Authors: Pidro Ajla, Ahmedegovic-Pjano Melisa, Mravicic Ivana, Grisevic Senad, Biscevic Alma, Pidro Aida
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Taiwan Journal of Ophthalmology
Subjects:
Online Access:http://www.e-tjo.org/article.asp?issn=2211-5056;year=2022;volume=12;issue=4;spage=452;epage=456;aulast=Ajla
_version_ 1811200242406653952
author Pidro Ajla
Ahmedegovic-Pjano Melisa
Mravicic Ivana
Grisevic Senad
Biscevic Alma
Pidro Aida
author_facet Pidro Ajla
Ahmedegovic-Pjano Melisa
Mravicic Ivana
Grisevic Senad
Biscevic Alma
Pidro Aida
author_sort Pidro Ajla
collection DOAJ
description PURPOSE: To compare and evaluate improvement in corrected distant visual acuity (CDVA) between myopia and hyperopia after laser in situ keratomileusis (LASIK) in adult patients with anisometropic amblyopia. MATERIALS AND METHODS: This prospective clinical study included 103 amblyopic eyes (103 patients), which underwent LASIK correction of refractive error from January 2013 to January 2018. Uncorrected distance visual acuity (UDVA), CDVA, spherical equivalent (SE), postoperative astigmatism, and intraocular pressure were evaluated at time points of 1, 6, and 12 months. RESULTS: Patients were divided into two groups according to refractive error. Group 1: Forty-six patients with myopia and Group 2: Fifty-seven patients with hyperopia. Mean CDVA (logarithm of the minimum angle of resolution [logMAR]) preoperatively was 0.23 ± 0.16 in Group 1 and 0.40 ± 0.19 in Group 2. Postoperative CDVA (logMAR) was 0.17 ± 0.13 in Group 1 and 0.32 ± 0.17 in Group 2. There was statistically significant increase in UDVA (P < 0.0001) postoperatively and no change during the follow-up period of 12 months in both groups. Group 1 showed more expectable results, 95% of variability SE achieved was dependent on SE intended (R2 = 0.95), while in Group 2, the percentage was slightly lower of expected 87% (R2 = 0.87). There was statistical significance in respect of CDVA change postoperatively and preoperatively in both groups. Correlation factors are low, in Group 1 r = −0.53 and in Group 2 r = −0.39. CONCLUSION: LASIK can improve CDVA in a considerable portion of amblyopic eyes, both myopic and hyperopic. Eyes with better initial CDVA and those with myopia were associated with greater improvement in postoperative CDVA.
first_indexed 2024-04-12T02:01:18Z
format Article
id doaj.art-70cf94e3206746978b166b4f4d545bae
institution Directory Open Access Journal
issn 2211-5056
2211-5072
language English
last_indexed 2024-04-12T02:01:18Z
publishDate 2022-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Taiwan Journal of Ophthalmology
spelling doaj.art-70cf94e3206746978b166b4f4d545bae2022-12-22T03:52:40ZengWolters Kluwer Medknow PublicationsTaiwan Journal of Ophthalmology2211-50562211-50722022-01-0112445245610.4103/tjo.tjo_22_21Laser keratomileusis in treatment of anisometropic amblyopia in adultsPidro AjlaAhmedegovic-Pjano MelisaMravicic IvanaGrisevic SenadBiscevic AlmaPidro AidaPURPOSE: To compare and evaluate improvement in corrected distant visual acuity (CDVA) between myopia and hyperopia after laser in situ keratomileusis (LASIK) in adult patients with anisometropic amblyopia. MATERIALS AND METHODS: This prospective clinical study included 103 amblyopic eyes (103 patients), which underwent LASIK correction of refractive error from January 2013 to January 2018. Uncorrected distance visual acuity (UDVA), CDVA, spherical equivalent (SE), postoperative astigmatism, and intraocular pressure were evaluated at time points of 1, 6, and 12 months. RESULTS: Patients were divided into two groups according to refractive error. Group 1: Forty-six patients with myopia and Group 2: Fifty-seven patients with hyperopia. Mean CDVA (logarithm of the minimum angle of resolution [logMAR]) preoperatively was 0.23 ± 0.16 in Group 1 and 0.40 ± 0.19 in Group 2. Postoperative CDVA (logMAR) was 0.17 ± 0.13 in Group 1 and 0.32 ± 0.17 in Group 2. There was statistically significant increase in UDVA (P < 0.0001) postoperatively and no change during the follow-up period of 12 months in both groups. Group 1 showed more expectable results, 95% of variability SE achieved was dependent on SE intended (R2 = 0.95), while in Group 2, the percentage was slightly lower of expected 87% (R2 = 0.87). There was statistical significance in respect of CDVA change postoperatively and preoperatively in both groups. Correlation factors are low, in Group 1 r = −0.53 and in Group 2 r = −0.39. CONCLUSION: LASIK can improve CDVA in a considerable portion of amblyopic eyes, both myopic and hyperopic. Eyes with better initial CDVA and those with myopia were associated with greater improvement in postoperative CDVA.http://www.e-tjo.org/article.asp?issn=2211-5056;year=2022;volume=12;issue=4;spage=452;epage=456;aulast=Ajlaamblyopiaanisometropialaser in situ keratomileusis
spellingShingle Pidro Ajla
Ahmedegovic-Pjano Melisa
Mravicic Ivana
Grisevic Senad
Biscevic Alma
Pidro Aida
Laser keratomileusis in treatment of anisometropic amblyopia in adults
Taiwan Journal of Ophthalmology
amblyopia
anisometropia
laser in situ keratomileusis
title Laser keratomileusis in treatment of anisometropic amblyopia in adults
title_full Laser keratomileusis in treatment of anisometropic amblyopia in adults
title_fullStr Laser keratomileusis in treatment of anisometropic amblyopia in adults
title_full_unstemmed Laser keratomileusis in treatment of anisometropic amblyopia in adults
title_short Laser keratomileusis in treatment of anisometropic amblyopia in adults
title_sort laser keratomileusis in treatment of anisometropic amblyopia in adults
topic amblyopia
anisometropia
laser in situ keratomileusis
url http://www.e-tjo.org/article.asp?issn=2211-5056;year=2022;volume=12;issue=4;spage=452;epage=456;aulast=Ajla
work_keys_str_mv AT pidroajla laserkeratomileusisintreatmentofanisometropicamblyopiainadults
AT ahmedegovicpjanomelisa laserkeratomileusisintreatmentofanisometropicamblyopiainadults
AT mravicicivana laserkeratomileusisintreatmentofanisometropicamblyopiainadults
AT grisevicsenad laserkeratomileusisintreatmentofanisometropicamblyopiainadults
AT biscevicalma laserkeratomileusisintreatmentofanisometropicamblyopiainadults
AT pidroaida laserkeratomileusisintreatmentofanisometropicamblyopiainadults