Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes

Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes

Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and A...

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Main Authors: Adriele Dandara Levorato-Vinche, Marcia de Souza Carvalho Melhem, Lucas Xavier Bonfietti, Iván de-la-Cruz-Chacón, Carmen Sílvia Fernandes Boaro, Alexandre Todorovic Fabro, Gisela Ferreira, Julhiany de Fátima da Silva, Daniela Carvalho dos Santos, Beatriz Aparecida Soares Pereira, Camila Marçon, Lariza Maza, Lídia Raquel de Carvalho, Rinaldo Poncio Mendes
Format: Article
Language:English
Published: SciELO 2022-09-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Liriodenine
Yeast
Fungi
Fungal cell ultrastructure
Cryptococcus spp.
Time-kill methodology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992022000100317&lng=en&tlng=en

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