First Coronavirus Active Survey in Rodents From the Canary Islands
Since the beginning of the 21st century five new coronaviruses inducing respiratory diseases in humans have been reported. These emergences has promoted research on coronaviruses in wildlife. We started the first eco-epidemiological study to screen the presence of coronaviruses circulating in mice a...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-08-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.708079/full |
| _version_ | 1818607689924608000 |
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| author | Abir Monastiri Abir Monastiri Natalia Martín-Carrillo Natalia Martín-Carrillo Pilar Foronda Pilar Foronda Elena Izquierdo-Rodríguez Elena Izquierdo-Rodríguez Carles Feliu Marc López-Roig Marc López-Roig Jordi Miquel Jordi Miquel Meriadeg Ar Gouilh Meriadeg Ar Gouilh Jordi Serra-Cobo Jordi Serra-Cobo |
| author_facet | Abir Monastiri Abir Monastiri Natalia Martín-Carrillo Natalia Martín-Carrillo Pilar Foronda Pilar Foronda Elena Izquierdo-Rodríguez Elena Izquierdo-Rodríguez Carles Feliu Marc López-Roig Marc López-Roig Jordi Miquel Jordi Miquel Meriadeg Ar Gouilh Meriadeg Ar Gouilh Jordi Serra-Cobo Jordi Serra-Cobo |
| author_sort | Abir Monastiri |
| collection | DOAJ |
| description | Since the beginning of the 21st century five new coronaviruses inducing respiratory diseases in humans have been reported. These emergences has promoted research on coronaviruses in wildlife. We started the first eco-epidemiological study to screen the presence of coronaviruses circulating in mice and rats of four Canary Islands. Between 2015 and 2019, we obtained fecal samples of three rodent species (150 Mus musculus, 109 Rattus rattus and 1 Rattus norvegicus) captured in urban and rural areas. Fecal samples were analyzed by nRT-PCR and the resulting sequences were compared to known diversity using Bayesian phylogenetic methods. We only found coronavirus RNA in house mice from El Hierro (10.53%), Tenerife (7.02%) and Lanzarote (5.26%) islands. All coronaviruses detected belong to the species Murine coronavirus belonging to the genus Betacoronavirus and subgenus Embecovirus, being all positive house mice captured in anthropogenic environment. The phylogenetic analysis shows that murine coronaviruses from the Canary Islands are related to European murine coronaviruses. Albeit data are still scarce in the region, the most probable origin of M. coronavirus present in the Canary Islands is continental Europe. According to temporal Bayesian phylogenetics, the differentiation between Canary and continental viruses seems to be quite recent. Moreover, murine coronaviruses from El Hierro, Tenerife and Lanzarote islands tend to segregate in different clades. This enlightens the potential role of rodents or other possibly invasive species in disseminating infectious diseases to remote places through exchanges with the continent. It is important to consider these aspects in the sanitary control of islands, for health and biodiversity preservation concerns. |
| first_indexed | 2024-12-16T14:30:45Z |
| format | Article |
| id | doaj.art-70d133de3cc34a34b955140a399e074a |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-16T14:30:45Z |
| publishDate | 2021-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-70d133de3cc34a34b955140a399e074a2022-12-21T22:28:15ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-08-01810.3389/fvets.2021.708079708079First Coronavirus Active Survey in Rodents From the Canary IslandsAbir Monastiri0Abir Monastiri1Natalia Martín-Carrillo2Natalia Martín-Carrillo3Pilar Foronda4Pilar Foronda5Elena Izquierdo-Rodríguez6Elena Izquierdo-Rodríguez7Carles Feliu8Marc López-Roig9Marc López-Roig10Jordi Miquel11Jordi Miquel12Meriadeg Ar Gouilh13Meriadeg Ar Gouilh14Jordi Serra-Cobo15Jordi Serra-Cobo16Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, SpainFaculty of Biology, Institut de Recerca de la Biodiversitat, University of Barcelona, Barcelona, SpainInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, La Laguna, SpainDepartment of Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, SpainInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, La Laguna, SpainDepartment of Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, SpainInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, La Laguna, SpainDepartment of Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, SpainDepartment of Biology, Health and Environment, Faculty of Pharmacy, University of Barcelona, Barcelona, SpainDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, SpainFaculty of Biology, Institut de Recerca de la Biodiversitat, University of Barcelona, Barcelona, SpainFaculty of Biology, Institut de Recerca de la Biodiversitat, University of Barcelona, Barcelona, SpainDepartment of Biology, Health and Environment, Faculty of Pharmacy, University of Barcelona, Barcelona, SpainNormandie Université, EA2656, Groupe de Recherche sur l'Adaptation Microbienne, Caen, FranceUniversity Hospital of Caen, Virology Department, Caen, FranceDepartment of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, SpainFaculty of Biology, Institut de Recerca de la Biodiversitat, University of Barcelona, Barcelona, SpainSince the beginning of the 21st century five new coronaviruses inducing respiratory diseases in humans have been reported. These emergences has promoted research on coronaviruses in wildlife. We started the first eco-epidemiological study to screen the presence of coronaviruses circulating in mice and rats of four Canary Islands. Between 2015 and 2019, we obtained fecal samples of three rodent species (150 Mus musculus, 109 Rattus rattus and 1 Rattus norvegicus) captured in urban and rural areas. Fecal samples were analyzed by nRT-PCR and the resulting sequences were compared to known diversity using Bayesian phylogenetic methods. We only found coronavirus RNA in house mice from El Hierro (10.53%), Tenerife (7.02%) and Lanzarote (5.26%) islands. All coronaviruses detected belong to the species Murine coronavirus belonging to the genus Betacoronavirus and subgenus Embecovirus, being all positive house mice captured in anthropogenic environment. The phylogenetic analysis shows that murine coronaviruses from the Canary Islands are related to European murine coronaviruses. Albeit data are still scarce in the region, the most probable origin of M. coronavirus present in the Canary Islands is continental Europe. According to temporal Bayesian phylogenetics, the differentiation between Canary and continental viruses seems to be quite recent. Moreover, murine coronaviruses from El Hierro, Tenerife and Lanzarote islands tend to segregate in different clades. This enlightens the potential role of rodents or other possibly invasive species in disseminating infectious diseases to remote places through exchanges with the continent. It is important to consider these aspects in the sanitary control of islands, for health and biodiversity preservation concerns.https://www.frontiersin.org/articles/10.3389/fvets.2021.708079/fullBetacoronavirusEmbecovirusMurine coronavirusrodentsCanary Islandscoronavirus |
| spellingShingle | Abir Monastiri Abir Monastiri Natalia Martín-Carrillo Natalia Martín-Carrillo Pilar Foronda Pilar Foronda Elena Izquierdo-Rodríguez Elena Izquierdo-Rodríguez Carles Feliu Marc López-Roig Marc López-Roig Jordi Miquel Jordi Miquel Meriadeg Ar Gouilh Meriadeg Ar Gouilh Jordi Serra-Cobo Jordi Serra-Cobo First Coronavirus Active Survey in Rodents From the Canary Islands Frontiers in Veterinary Science Betacoronavirus Embecovirus Murine coronavirus rodents Canary Islands coronavirus |
| title | First Coronavirus Active Survey in Rodents From the Canary Islands |
| title_full | First Coronavirus Active Survey in Rodents From the Canary Islands |
| title_fullStr | First Coronavirus Active Survey in Rodents From the Canary Islands |
| title_full_unstemmed | First Coronavirus Active Survey in Rodents From the Canary Islands |
| title_short | First Coronavirus Active Survey in Rodents From the Canary Islands |
| title_sort | first coronavirus active survey in rodents from the canary islands |
| topic | Betacoronavirus Embecovirus Murine coronavirus rodents Canary Islands coronavirus |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2021.708079/full |
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