3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequis...

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Main Authors: Soroosh Derakhshanfar, Rene Mbeleck, Kaige Xu, Xingying Zhang, Wen Zhong, Malcolm Xing
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-06-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X17301068
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author Soroosh Derakhshanfar
Rene Mbeleck
Kaige Xu
Xingying Zhang
Wen Zhong
Malcolm Xing
author_facet Soroosh Derakhshanfar
Rene Mbeleck
Kaige Xu
Xingying Zhang
Wen Zhong
Malcolm Xing
author_sort Soroosh Derakhshanfar
collection DOAJ
description 3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks.
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spelling doaj.art-70d14387b47a47aab2f7be3dc178dab92024-04-16T12:12:23ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2018-06-013214415610.1016/j.bioactmat.2017.11.0083D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advancesSoroosh Derakhshanfar0Rene Mbeleck1Kaige Xu2Xingying Zhang3Wen Zhong4Malcolm Xing5Department of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, CanadaDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, CanadaDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, CanadaDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, CanadaDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, R3T 2N2, CanadaDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks.http://www.sciencedirect.com/science/article/pii/S2452199X17301068BioprintingHydrogelExtrusionInkjetStereolithographyLaser-assistedReview3D printing
spellingShingle Soroosh Derakhshanfar
Rene Mbeleck
Kaige Xu
Xingying Zhang
Wen Zhong
Malcolm Xing
3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
Bioactive Materials
Bioprinting
Hydrogel
Extrusion
Inkjet
Stereolithography
Laser-assisted
Review
3D printing
title 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_full 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_fullStr 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_full_unstemmed 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_short 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_sort 3d bioprinting for biomedical devices and tissue engineering a review of recent trends and advances
topic Bioprinting
Hydrogel
Extrusion
Inkjet
Stereolithography
Laser-assisted
Review
3D printing
url http://www.sciencedirect.com/science/article/pii/S2452199X17301068
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