Determination of S- and R-Amlodipine in Rat Plasma using LC-MS/MS After Oral Administration of S-Amlodipine and Racemic Amlodipine
The pharmacokinetic properties of S-amlodipine were studied using racemic amlodipine and single S-enantiomer(SK310) administration to rats. Plasma levels of the drug were determined using chiral liquid chromatography coupled with tandemmass spectrometry following solid phase extraction. The stereosp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society for Mass Spectrometry
2011-12-01
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| Series: | Mass Spectrometry Letters |
| Online Access: | http://Amlodipine, LC-MS/MS, Pharmacokinetics, Rat plasma |