Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review
With the rapid outbreak of the coronavirus disease 2019 (COVID-19) pandemic, considerable concerns about the safety of systemic treatments of immune-mediated dermatologic disorders has been raised by dermatologists and their patients. We aimed to perform a rapid review of latest American and Europea...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Dermatologica Sinica |
| Subjects: | |
| Online Access: | http://www.dermsinica.org/article.asp?issn=1027-8117;year=2022;volume=40;issue=2;spage=67;epage=70;aulast=Yu |
| _version_ | 1818474381131644928 |
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| author | Chia-Ling Yu Yu-Ting Lin Ching-Chi Chi |
| author_facet | Chia-Ling Yu Yu-Ting Lin Ching-Chi Chi |
| author_sort | Chia-Ling Yu |
| collection | DOAJ |
| description | With the rapid outbreak of the coronavirus disease 2019 (COVID-19) pandemic, considerable concerns about the safety of systemic treatments of immune-mediated dermatologic disorders has been raised by dermatologists and their patients. We aimed to perform a rapid review of latest American and European guidelines on the use of systemic treatments in patients with immune-mediated dermatologic disorders and confirmed COVID-19 infection and to provide recommendations to inform practice. Based on the current limited guidelines and evidence, systemic corticosteroids should not be abruptly discontinued and the lowest effective dose should be continued. Systemic immunosuppressants (including methotrexate, cyclosporine, azathioprine, cyclophosphamide, and leflunomide), biologics, and sulfasalazine should be withheld in patients with confirmed COVID-19 infection. Whether to continue Janus kinase inhibitors should be determined following a shared decision-making process between dermatologists and patients after considering patients' medical conditions and risk for severe COVID. |
| first_indexed | 2024-04-14T04:36:11Z |
| format | Article |
| id | doaj.art-70db41457e0a4abeadb038741e231248 |
| institution | Directory Open Access Journal |
| issn | 1027-8117 2223-330X |
| language | English |
| last_indexed | 2024-04-14T04:36:11Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dermatologica Sinica |
| spelling | doaj.art-70db41457e0a4abeadb038741e2312482022-12-22T02:11:51ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172223-330X2022-01-01402677010.4103/1027-8117.349030Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid reviewChia-Ling YuYu-Ting LinChing-Chi ChiWith the rapid outbreak of the coronavirus disease 2019 (COVID-19) pandemic, considerable concerns about the safety of systemic treatments of immune-mediated dermatologic disorders has been raised by dermatologists and their patients. We aimed to perform a rapid review of latest American and European guidelines on the use of systemic treatments in patients with immune-mediated dermatologic disorders and confirmed COVID-19 infection and to provide recommendations to inform practice. Based on the current limited guidelines and evidence, systemic corticosteroids should not be abruptly discontinued and the lowest effective dose should be continued. Systemic immunosuppressants (including methotrexate, cyclosporine, azathioprine, cyclophosphamide, and leflunomide), biologics, and sulfasalazine should be withheld in patients with confirmed COVID-19 infection. Whether to continue Janus kinase inhibitors should be determined following a shared decision-making process between dermatologists and patients after considering patients' medical conditions and risk for severe COVID.http://www.dermsinica.org/article.asp?issn=1027-8117;year=2022;volume=40;issue=2;spage=67;epage=70;aulast=Yuatopic dermatitisautoimmune bullous dermatosiscovid-19immune-mediated dermatologic disorderpsoriasis |
| spellingShingle | Chia-Ling Yu Yu-Ting Lin Ching-Chi Chi Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review Dermatologica Sinica atopic dermatitis autoimmune bullous dermatosis covid-19 immune-mediated dermatologic disorder psoriasis |
| title | Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review |
| title_full | Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review |
| title_fullStr | Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review |
| title_full_unstemmed | Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review |
| title_short | Recommendations on use of systemic treatments for immune-mediated dermatologic disorders in patients with confirmed COVID-19 infection: A rapid review |
| title_sort | recommendations on use of systemic treatments for immune mediated dermatologic disorders in patients with confirmed covid 19 infection a rapid review |
| topic | atopic dermatitis autoimmune bullous dermatosis covid-19 immune-mediated dermatologic disorder psoriasis |
| url | http://www.dermsinica.org/article.asp?issn=1027-8117;year=2022;volume=40;issue=2;spage=67;epage=70;aulast=Yu |
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