Loss of pericyte smoothened activity in mice with genetic deficiency of leptin

Loss of pericyte smoothened activity in mice with genetic deficiency of leptin

Abstract Background Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy availability at the cellular level. The satiety factor, leptin, is a key com...

Full description

Bibliographic Details
Main Authors: Guanhua Xie, Marzena Swiderska-Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory A. Michelotti, Richard T. Premont, Anna Mae Diehl
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Cell Biology
Subjects:
Obesity
Leptin
Hedgehog
Pericytes
Energy balance
Tissue repair
Online Access:http://link.springer.com/article/10.1186/s12860-017-0135-y

Similar Items

Similar Items