The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance

The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance

Advances in functional imaging are supporting neurosurgery and radiotherapy for glioblastoma, which still remains the most aggressive brain tumor with poor prognosis. The typical infiltration pattern of glioblastoma, which impedes a complete surgical resection, is coupled with a high rate of invasiv...

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Bibliographic Details
Main Authors: Filippo Torrisi, Nunzio Vicario, Federica M. Spitale, Francesco P. Cammarata, Luigi Minafra, Lucia Salvatorelli, Giorgio Russo, Giacomo Cuttone, Samuel Valable, Rosario Gulino, Gaetano Magro, Rosalba Parenti
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
Glioblastoma
hypoxia
radioresistance
invasion
SRC tyrosine kinase
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/12/10/2860

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