Sensitive Detection of Ciguatoxins Using a Neuroblastoma Cell-Based Assay with Voltage-Gated Potassium Channel Inhibitors

Sensitive Detection of Ciguatoxins Using a Neuroblastoma Cell-Based Assay with Voltage-Gated Potassium Channel Inhibitors

Ciguatoxins (CTXs) are neurotoxins responsible for ciguatera poisoning (CP), which affects more than 50,000 people worldwide annually. The development of analytical methods to prevent CP is a pressing global issue, and the N2a assay is one of the most promising methods for detecting CTXs. CTXs are h...

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Bibliografiske detaljer
Main Authors: Toshiaki Yokozeki, Madoka Kawabata, Kazuhiro Fujita, Masahiro Hirama, Takeshi Tsumuraya
Format: Article
Sprog:English
Udgivet: MDPI AG 2024-02-01
Serier:Toxins
Fag:
ciguatoxins
neuroblastoma cell-based assay
voltage-gated sodium channels
voltage-gated potassium channels
4-aminopyridine
tetraethylammonium chloride
Online adgang:https://www.mdpi.com/2072-6651/16/3/118

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https://www.mdpi.com/2072-6651/16/3/118

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