National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements
The pervasive nature of infections causing major outbreaks have elevated biosafety and biosecurity as a fundamental component for resilient national laboratory systems. In response to international health security demands, the Global Health Security Agenda emphasizes biosafety as one of the prerequi...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-07-01
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| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2021.609107/full |
| _version_ | 1818917607354400768 |
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| author | Arnaud Orelle Abdoulaye Nikiema Arsen Zakaryan Adilya A. Albetkova Mark A. Rayfield Leonard F. Peruski Antoine Pierson Obert Kachuwaire |
| author_facet | Arnaud Orelle Abdoulaye Nikiema Arsen Zakaryan Adilya A. Albetkova Mark A. Rayfield Leonard F. Peruski Antoine Pierson Obert Kachuwaire |
| author_sort | Arnaud Orelle |
| collection | DOAJ |
| description | The pervasive nature of infections causing major outbreaks have elevated biosafety and biosecurity as a fundamental component for resilient national laboratory systems. In response to international health security demands, the Global Health Security Agenda emphasizes biosafety as one of the prerequisites to respond effectively to infectious disease threats. However, biosafety management systems (BMS) in low-medium income countries (LMIC) remain weak due to fragmented implementation strategies. In addition, inefficiencies in implementation have been due to limited resources, inadequate technical expertise, high equipment costs, and insufficient political will. Here we propose an approach to developing a strong, self-sustaining BMS based on extensive experience in LMICs. A conceptual framework incorporating 15 key components to guide implementers, national laboratory leaders, global health security experts in building a BMS is presented. This conceptual framework provides a holistic and logical approach to the development of a BMS with all critical elements. It includes a flexible planning matrix with timelines easily adaptable to different country contexts as examples, as well as resources that are critical for developing sustainable technical expertise. |
| first_indexed | 2024-12-20T00:36:45Z |
| format | Article |
| id | doaj.art-70e6b80f2c394aa3a0721826ef464b12 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-12-20T00:36:45Z |
| publishDate | 2021-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-70e6b80f2c394aa3a0721826ef464b122022-12-21T19:59:43ZengFrontiers Media S.A.Frontiers in Public Health2296-25652021-07-01910.3389/fpubh.2021.609107609107National Biosafety Management System: A Combined Framework Approach Based on 15 Key ElementsArnaud Orelle0Abdoulaye Nikiema1Arsen Zakaryan2Adilya A. Albetkova3Mark A. Rayfield4Leonard F. Peruski5Antoine Pierson6Obert Kachuwaire7Integrated Quality Laboratory Services, Lyon, FranceIntegrated Quality Laboratory Services, Lyon, FranceIntegrated Quality Laboratory Services, Lyon, FranceDivision of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United StatesDivision of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United StatesDivision of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United StatesIntegrated Quality Laboratory Services, Lyon, FranceIntegrated Quality Laboratory Services, Lyon, FranceThe pervasive nature of infections causing major outbreaks have elevated biosafety and biosecurity as a fundamental component for resilient national laboratory systems. In response to international health security demands, the Global Health Security Agenda emphasizes biosafety as one of the prerequisites to respond effectively to infectious disease threats. However, biosafety management systems (BMS) in low-medium income countries (LMIC) remain weak due to fragmented implementation strategies. In addition, inefficiencies in implementation have been due to limited resources, inadequate technical expertise, high equipment costs, and insufficient political will. Here we propose an approach to developing a strong, self-sustaining BMS based on extensive experience in LMICs. A conceptual framework incorporating 15 key components to guide implementers, national laboratory leaders, global health security experts in building a BMS is presented. This conceptual framework provides a holistic and logical approach to the development of a BMS with all critical elements. It includes a flexible planning matrix with timelines easily adaptable to different country contexts as examples, as well as resources that are critical for developing sustainable technical expertise.https://www.frontiersin.org/articles/10.3389/fpubh.2021.609107/fullbiosafetysafetybiosecuritybioriskframeworkGlobal Health Security Agenda |
| spellingShingle | Arnaud Orelle Abdoulaye Nikiema Arsen Zakaryan Adilya A. Albetkova Mark A. Rayfield Leonard F. Peruski Antoine Pierson Obert Kachuwaire National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements Frontiers in Public Health biosafety safety biosecurity biorisk framework Global Health Security Agenda |
| title | National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements |
| title_full | National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements |
| title_fullStr | National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements |
| title_full_unstemmed | National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements |
| title_short | National Biosafety Management System: A Combined Framework Approach Based on 15 Key Elements |
| title_sort | national biosafety management system a combined framework approach based on 15 key elements |
| topic | biosafety safety biosecurity biorisk framework Global Health Security Agenda |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2021.609107/full |
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