Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study

Background: Understanding biological causes of death and sociocultural factors that influence survival outcomes is crucial to reducing mortality in low-resource settings. Verbal and Social Autopsy instruments (VASAs) query family members about events leading up to an individual's death, resulti...

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Main Authors: Amy Blasini, MD, Peter Waiswa, PhD, Ann Wolski, BA, Philip Wanduru, PhD, Chelsea Finkbeiner, BS, Lucky Amutuhaire, BA, Cheryl A Moyer, PhD
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X22001395
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author Amy Blasini, MD
Peter Waiswa, PhD
Ann Wolski, BA
Philip Wanduru, PhD
Chelsea Finkbeiner, BS
Lucky Amutuhaire, BA
Cheryl A Moyer, PhD
author_facet Amy Blasini, MD
Peter Waiswa, PhD
Ann Wolski, BA
Philip Wanduru, PhD
Chelsea Finkbeiner, BS
Lucky Amutuhaire, BA
Cheryl A Moyer, PhD
author_sort Amy Blasini, MD
collection DOAJ
description Background: Understanding biological causes of death and sociocultural factors that influence survival outcomes is crucial to reducing mortality in low-resource settings. Verbal and Social Autopsy instruments (VASAs) query family members about events leading up to an individual's death, resulting in quantitative, categorical data. We aimed to determine the value of a supplemental in-depth interview (known as VASA-QUAL) that generated detailed qualitative data in understanding childhood deaths. Methods: This cross-sectional study was conducted in Kawaala and Nakulabye in Kampala, Uganda between Feb 6 and March 7, 2020, using 20 village health team members to assist in the identification and recruitment of families within which a children younger than 5 years had died within the preceding 6 months. Family members were interviewed by a trained, local researcher who conducted the quantitative VASA and the VASA-QUAL in-depth interview. Quantitative data were analysed using Stata (v16.0), and qualitative data were transcribed into English and analysed using NVivo (v12.0). Three coders compared quantitative variables from the VASA with qualitative variables from the VASA-QUAL using a rubric of eight key indicators related to symptom recognition, decision making, care seeking, and treatments given, derived from the Pathways to Survival framework. Agreement across sources and new insights from qualitative data were recorded. Findings: 48 VASAs were conducted, reflecting 48 deaths of children between the ages of 1 month and 3 days to 52 months. Agreement on key indicators ranged from 77% (for illness recognition) to 100% (for following provider referral recommendations). The qualitative component added or clarified information about pediatric illness and care-seeking across all indicators, including information about recognition of illness (96% of cases), care-seeking decisions (81%), whether home care was provided (75%), and choice of outside care (92%). The qualitative interviews frequently included symptoms that were missing or denied in the quantitative VASA, and they often clarified the chronological order of symptoms identified via VASA. Many qualitative interviews described complicated mechanisms of decision making, involving multiple key players, which were not adequately captured in the quantitative survey. Interpretation: Supplementing quantitative VASA tools with an in-depth VASA-QUAL interview provided important additional information. Supplemental qualitative interviews are an important tool for understanding the complexity of events leading up to childhood deaths. Funding: The Northern Pacific Global Health Research Training Consortium, Fogarty International Center at the National Institutes of Health.
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spelling doaj.art-70e8bf4b8bbd42c6885cf13ebe2026fb2022-12-21T23:46:33ZengElsevierThe Lancet Global Health2214-109X2022-03-0110S10Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional studyAmy Blasini, MD0Peter Waiswa, PhD1Ann Wolski, BA2Philip Wanduru, PhD3Chelsea Finkbeiner, BS4Lucky Amutuhaire, BA5Cheryl A Moyer, PhD6University of Michigan, Ann Arbor, MI, USA; Correspondence to: Dr Amy Blasini, University of Michigan, Ann Arbor, MI 48109, USAMakerere University, Kampala, UgandaUniversity of Michigan, Ann Arbor, MI, USAMakerere University, Kampala, UgandaUniversity of Michigan, Ann Arbor, MI, USAMakerere University, Kampala, UgandaUniversity of Michigan, Ann Arbor, MI, USABackground: Understanding biological causes of death and sociocultural factors that influence survival outcomes is crucial to reducing mortality in low-resource settings. Verbal and Social Autopsy instruments (VASAs) query family members about events leading up to an individual's death, resulting in quantitative, categorical data. We aimed to determine the value of a supplemental in-depth interview (known as VASA-QUAL) that generated detailed qualitative data in understanding childhood deaths. Methods: This cross-sectional study was conducted in Kawaala and Nakulabye in Kampala, Uganda between Feb 6 and March 7, 2020, using 20 village health team members to assist in the identification and recruitment of families within which a children younger than 5 years had died within the preceding 6 months. Family members were interviewed by a trained, local researcher who conducted the quantitative VASA and the VASA-QUAL in-depth interview. Quantitative data were analysed using Stata (v16.0), and qualitative data were transcribed into English and analysed using NVivo (v12.0). Three coders compared quantitative variables from the VASA with qualitative variables from the VASA-QUAL using a rubric of eight key indicators related to symptom recognition, decision making, care seeking, and treatments given, derived from the Pathways to Survival framework. Agreement across sources and new insights from qualitative data were recorded. Findings: 48 VASAs were conducted, reflecting 48 deaths of children between the ages of 1 month and 3 days to 52 months. Agreement on key indicators ranged from 77% (for illness recognition) to 100% (for following provider referral recommendations). The qualitative component added or clarified information about pediatric illness and care-seeking across all indicators, including information about recognition of illness (96% of cases), care-seeking decisions (81%), whether home care was provided (75%), and choice of outside care (92%). The qualitative interviews frequently included symptoms that were missing or denied in the quantitative VASA, and they often clarified the chronological order of symptoms identified via VASA. Many qualitative interviews described complicated mechanisms of decision making, involving multiple key players, which were not adequately captured in the quantitative survey. Interpretation: Supplementing quantitative VASA tools with an in-depth VASA-QUAL interview provided important additional information. Supplemental qualitative interviews are an important tool for understanding the complexity of events leading up to childhood deaths. Funding: The Northern Pacific Global Health Research Training Consortium, Fogarty International Center at the National Institutes of Health.http://www.sciencedirect.com/science/article/pii/S2214109X22001395
spellingShingle Amy Blasini, MD
Peter Waiswa, PhD
Ann Wolski, BA
Philip Wanduru, PhD
Chelsea Finkbeiner, BS
Lucky Amutuhaire, BA
Cheryl A Moyer, PhD
Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
The Lancet Global Health
title Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
title_full Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
title_fullStr Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
title_full_unstemmed Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
title_short Comparing quantitative and qualitative verbal and social autopsy tools for under-5 deaths in Uganda: a cross-sectional study
title_sort comparing quantitative and qualitative verbal and social autopsy tools for under 5 deaths in uganda a cross sectional study
url http://www.sciencedirect.com/science/article/pii/S2214109X22001395
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