Effects of dipole position, orientation and noise on the accuracy of EEG source localization
<p>Abstract</p> <p>Background</p> <p>The electroencephalogram (EEG) reflects the electrical activity in the brain on the surface of scalp. A major challenge in this field is the localization of sources in the brain responsible for eliciting the EEG signal measured at th...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2003-06-01
|
| Series: | BioMedical Engineering OnLine |
| Online Access: | http://www.biomedical-engineering-online.com/content/2/1/14 |
| _version_ | 1818533559694000128 |
|---|---|
| author | Connolly JF Gates Larry Stroink Gerhard Whittingstall Kevin Finley Allen |
| author_facet | Connolly JF Gates Larry Stroink Gerhard Whittingstall Kevin Finley Allen |
| author_sort | Connolly JF |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The electroencephalogram (EEG) reflects the electrical activity in the brain on the surface of scalp. A major challenge in this field is the localization of sources in the brain responsible for eliciting the EEG signal measured at the scalp. In order to estimate the location of these sources, one must correctly model the sources, i.e., dipoles, as well as the volume conductor in which the resulting currents flow. In this study, we investigate the effects of dipole depth and orientation on source localization with varying sets of simulated random noise in 4 realistic head models.</p> <p>Methods</p> <p>Dipole simulations were performed using realistic head models and using the boundary element method (BEM). In all, 92 dipole locations placed in temporal and parietal regions of the head with varying depth and orientation were investigated along with 6 different levels of simulated random noise. Localization errors due to dipole depth, orientation and noise were investigated.</p> <p>Results</p> <p>The results indicate that there are no significant differences in localization error due tangential and radial dipoles. With high levels of simulated Gaussian noise, localization errors are depth-dependant. For low levels of added noise, errors are similar for both deep and superficial sources.</p> <p>Conclusion</p> <p>It was found that if the signal-to-noise ratio is above a certain threshold, localization errors in realistic head models are, on average the same for deep and superficial sources. As the noise increases, localization errors increase, particularly for deep sources.</p> |
| first_indexed | 2024-12-11T18:00:19Z |
| format | Article |
| id | doaj.art-70efa292cf9d42368472f1a6736539e9 |
| institution | Directory Open Access Journal |
| issn | 1475-925X |
| language | English |
| last_indexed | 2024-12-11T18:00:19Z |
| publishDate | 2003-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BioMedical Engineering OnLine |
| spelling | doaj.art-70efa292cf9d42368472f1a6736539e92022-12-22T00:55:54ZengBMCBioMedical Engineering OnLine1475-925X2003-06-01211410.1186/1475-925X-2-14Effects of dipole position, orientation and noise on the accuracy of EEG source localizationConnolly JFGates LarryStroink GerhardWhittingstall KevinFinley Allen<p>Abstract</p> <p>Background</p> <p>The electroencephalogram (EEG) reflects the electrical activity in the brain on the surface of scalp. A major challenge in this field is the localization of sources in the brain responsible for eliciting the EEG signal measured at the scalp. In order to estimate the location of these sources, one must correctly model the sources, i.e., dipoles, as well as the volume conductor in which the resulting currents flow. In this study, we investigate the effects of dipole depth and orientation on source localization with varying sets of simulated random noise in 4 realistic head models.</p> <p>Methods</p> <p>Dipole simulations were performed using realistic head models and using the boundary element method (BEM). In all, 92 dipole locations placed in temporal and parietal regions of the head with varying depth and orientation were investigated along with 6 different levels of simulated random noise. Localization errors due to dipole depth, orientation and noise were investigated.</p> <p>Results</p> <p>The results indicate that there are no significant differences in localization error due tangential and radial dipoles. With high levels of simulated Gaussian noise, localization errors are depth-dependant. For low levels of added noise, errors are similar for both deep and superficial sources.</p> <p>Conclusion</p> <p>It was found that if the signal-to-noise ratio is above a certain threshold, localization errors in realistic head models are, on average the same for deep and superficial sources. As the noise increases, localization errors increase, particularly for deep sources.</p>http://www.biomedical-engineering-online.com/content/2/1/14 |
| spellingShingle | Connolly JF Gates Larry Stroink Gerhard Whittingstall Kevin Finley Allen Effects of dipole position, orientation and noise on the accuracy of EEG source localization BioMedical Engineering OnLine |
| title | Effects of dipole position, orientation and noise on the accuracy of EEG source localization |
| title_full | Effects of dipole position, orientation and noise on the accuracy of EEG source localization |
| title_fullStr | Effects of dipole position, orientation and noise on the accuracy of EEG source localization |
| title_full_unstemmed | Effects of dipole position, orientation and noise on the accuracy of EEG source localization |
| title_short | Effects of dipole position, orientation and noise on the accuracy of EEG source localization |
| title_sort | effects of dipole position orientation and noise on the accuracy of eeg source localization |
| url | http://www.biomedical-engineering-online.com/content/2/1/14 |
| work_keys_str_mv | AT connollyjf effectsofdipolepositionorientationandnoiseontheaccuracyofeegsourcelocalization AT gateslarry effectsofdipolepositionorientationandnoiseontheaccuracyofeegsourcelocalization AT stroinkgerhard effectsofdipolepositionorientationandnoiseontheaccuracyofeegsourcelocalization AT whittingstallkevin effectsofdipolepositionorientationandnoiseontheaccuracyofeegsourcelocalization AT finleyallen effectsofdipolepositionorientationandnoiseontheaccuracyofeegsourcelocalization |