Action of neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi venom, on skeletal muscle: an ultrastructural and immunocytochemistry study

The damaging effects of neuwiedase, a non-hemorrhagic snake venom metalloproteinase from P-I class, on gastrocnemius muscle are studied herein. Following neuwiedase injection, ultrastructural alterations were detected early showing disarrangement of skeletal muscle fibers (characterized by discontin...

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Bibliographic Details
Main Authors: C Baldo, MJ Ferreira, DS Lopes, LFM Izidoro, AO Gomes, EAV Ferro, A Hamaguchi, MI Homsi-Brandeburgo, VM Rodrigues
Format: Article
Language:English
Published: SciELO 2010-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300013