Novel strategy for selection of monoclonal antibodies against highly conserved antigens: phage library panning against ephrin-B2 displayed on yeast.
Ephrin-B2 is predominately expressed in endothelium of arterial origin, involved in developmental angiogenesis and neovasculature formation through its interaction with EphB4. Despite its importance in physiology and pathological conditions, it has been challenging to produce monoclonal antibodies a...
Main Authors: | Xiaoling Gu, Yogindra Vedvyas, Xiaoyue Chen, Tanwi Kaushik, Chang-Il Hwang, Xuebo Hu, Alexander Y Nikitin, Moonsoo M Jin |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3264634?pdf=render |
Similar Items
-
Subtractive panning for the isolation of monoclonal PEPITEM peptide antibody by phage display
by: Mohammed Alassiri, et al.
Published: (2023-08-01) -
Characterization of Monoclonal Antibodies against Bovine herpesvirus type 1 selected by Phage Display Technology
by: Greice Japolla, et al.
Published: (2017-11-01) -
Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein.
by: Zhifeng Chen, et al.
Published: (2016-01-01) -
Characterization of Monoclonal Antibodies against Bovine herpesvirus type 1 selected by Phage Display Technology
by: Greice Japolla, et al.
Published: (2017-11-01) -
Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response
by: Yanping Yang, et al.
Published: (2024-03-01)