Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering
The repair of severe bone defects is still a formidable clinical challenge, requiring the implantation of bone grafts or bone substitute materials. The development of three-dimensional (3D) bioprinting has received considerable attention in bone tissue engineering over the past decade. However, 3D p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/1/814 |
| _version_ | 1797625546341875712 |
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| author | Xinwei Zhang Yixin Yang Zhen Yang Rui Ma Maierhaba Aimaijiang Jing Xu Yidi Zhang Yanmin Zhou |
| author_facet | Xinwei Zhang Yixin Yang Zhen Yang Rui Ma Maierhaba Aimaijiang Jing Xu Yidi Zhang Yanmin Zhou |
| author_sort | Xinwei Zhang |
| collection | DOAJ |
| description | The repair of severe bone defects is still a formidable clinical challenge, requiring the implantation of bone grafts or bone substitute materials. The development of three-dimensional (3D) bioprinting has received considerable attention in bone tissue engineering over the past decade. However, 3D printing has a limitation. It only takes into account the original form of the printed scaffold, which is inanimate and static, and is not suitable for dynamic organisms. With the emergence of stimuli-responsive materials, four-dimensional (4D) printing has become the next-generation solution for biological tissue engineering. It combines the concept of time with three-dimensional printing. Over time, 4D-printed scaffolds change their appearance or function in response to environmental stimuli (physical, chemical, and biological). In conclusion, 4D printing is the change of the fourth dimension (time) in 3D printing, which provides unprecedented potential for bone tissue repair. In this review, we will discuss the latest research on shape memory materials and 4D printing in bone tissue repair. |
| first_indexed | 2024-03-11T09:57:54Z |
| format | Article |
| id | doaj.art-70f44fd920a8483e9f3fba19ef78ac97 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T09:57:54Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-70f44fd920a8483e9f3fba19ef78ac972023-11-16T15:38:53ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-01-0124181410.3390/ijms24010814Four-Dimensional Printing and Shape Memory Materials in Bone Tissue EngineeringXinwei Zhang0Yixin Yang1Zhen Yang2Rui Ma3Maierhaba Aimaijiang4Jing Xu5Yidi Zhang6Yanmin Zhou7Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaSchool of Stomatology, Jilin University, Changchun 130021, ChinaSchool of Stomatology, Jilin University, Changchun 130021, ChinaJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, ChinaThe repair of severe bone defects is still a formidable clinical challenge, requiring the implantation of bone grafts or bone substitute materials. The development of three-dimensional (3D) bioprinting has received considerable attention in bone tissue engineering over the past decade. However, 3D printing has a limitation. It only takes into account the original form of the printed scaffold, which is inanimate and static, and is not suitable for dynamic organisms. With the emergence of stimuli-responsive materials, four-dimensional (4D) printing has become the next-generation solution for biological tissue engineering. It combines the concept of time with three-dimensional printing. Over time, 4D-printed scaffolds change their appearance or function in response to environmental stimuli (physical, chemical, and biological). In conclusion, 4D printing is the change of the fourth dimension (time) in 3D printing, which provides unprecedented potential for bone tissue repair. In this review, we will discuss the latest research on shape memory materials and 4D printing in bone tissue repair.https://www.mdpi.com/1422-0067/24/1/8143D printing4D printingbone regenerationshape memory materialstissue engineering |
| spellingShingle | Xinwei Zhang Yixin Yang Zhen Yang Rui Ma Maierhaba Aimaijiang Jing Xu Yidi Zhang Yanmin Zhou Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering International Journal of Molecular Sciences 3D printing 4D printing bone regeneration shape memory materials tissue engineering |
| title | Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering |
| title_full | Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering |
| title_fullStr | Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering |
| title_full_unstemmed | Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering |
| title_short | Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering |
| title_sort | four dimensional printing and shape memory materials in bone tissue engineering |
| topic | 3D printing 4D printing bone regeneration shape memory materials tissue engineering |
| url | https://www.mdpi.com/1422-0067/24/1/814 |
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