Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors
The immunostimulatory properties of TLR7/8 agonists, such as resiquimod, have been exploited for cancer immunotherapy. Here, the authors design platelet membrane-cloaked nanoparticles for selective intratumoral delivery of resiquimod, resulting in potent anti-tumor immune response in a range of prec...
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Bibliographic Details
| Main Authors: |
Baharak Bahmani,
Hua Gong,
Brian T. Luk,
Kristofer J. Haushalter,
Ethel DeTeresa,
Mark Previti,
Jiarong Zhou,
Weiwei Gao,
Jack D. Bui,
Liangfang Zhang,
Ronnie H. Fang,
Jie Zhang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-22311-z
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