Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study
Introduction: The presence of existing osteoporotic vertebral fracture (OVF) increases the mortality risk. However, the influence of the characteristics of OVF is unclear. This study aimed to investigate the influence of new OVF on patients’ long-term prognosis using our past cohort study. Method: T...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-02-01
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| Series: | Journal of Orthopaedic Surgery |
| Online Access: | https://doi.org/10.1177/2309499021994969 |
| _version_ | 1818866143297798144 |
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| author | Shinji Takahashi Hidetomi Terai Masatoshi Hoshino Tadao Tsujio Akinobu Suzuki Takashi Namikawa Minori Kato Akira Matsumura Kazushi Takayama Hiromitsu Toyoda Koji Tamai Shoichiro Ohyama Yusuke Hori Akito Yabu Hiroaki Nakamura |
| author_facet | Shinji Takahashi Hidetomi Terai Masatoshi Hoshino Tadao Tsujio Akinobu Suzuki Takashi Namikawa Minori Kato Akira Matsumura Kazushi Takayama Hiromitsu Toyoda Koji Tamai Shoichiro Ohyama Yusuke Hori Akito Yabu Hiroaki Nakamura |
| author_sort | Shinji Takahashi |
| collection | DOAJ |
| description | Introduction: The presence of existing osteoporotic vertebral fracture (OVF) increases the mortality risk. However, the influence of the characteristics of OVF is unclear. This study aimed to investigate the influence of new OVF on patients’ long-term prognosis using our past cohort study. Method: This is an extension study of our cohort study carried out between 2005 and 2007. In the present extension study, of 420 patients, 197 whose contact information was available at the 6-month follow-up were included in the telephone survey in 2018. Five patients refused to participate in the survey, and 82 could not be contacted. Eventually, 110 patients were enrolled. Of the Demographic data, radiological findings, medical history, and clinical outcome were investigated at injury onset and at the 6-month follow-up. A proportional hazard model was used to investigate the risk factors for mortality. Results: Among 110 patients, 33 died. Male sex and low body mass index (BMI <18.5 kg/m 2 ) were significant risk factors for mortality [hazard ratio (HR) = 6.40, 1.01–40.50; 5.24, 1.44–19.04, respectively]. The history of stroke and liver disease increased the risk of mortality (HR = 13.37, 1.93–92.7; 6.62, 1.15–38.14, respectively). As regards radiological findings, local kyphosis progression per 1° or ≥7° were significant risk factors of mortality (HR = 1.20, 1.06–1.36; 5.38, 1.81–16.03, respectively). Conclusions: A telephone survey at 12 years after the occurrence of OVF analyzed risk factors for mortality and showed that a progression of local kyphosis in fractures between injury onset and 6 months after injury was a risk factor of poor prognosis. |
| first_indexed | 2024-12-19T10:58:45Z |
| format | Article |
| id | doaj.art-70f70cc0881c4a899fb812d075360b67 |
| institution | Directory Open Access Journal |
| issn | 2309-4990 |
| language | English |
| last_indexed | 2024-12-19T10:58:45Z |
| publishDate | 2021-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Orthopaedic Surgery |
| spelling | doaj.art-70f70cc0881c4a899fb812d075360b672022-12-21T20:24:42ZengSAGE PublishingJournal of Orthopaedic Surgery2309-49902021-02-012910.1177/2309499021994969Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort studyShinji Takahashi0Hidetomi Terai1Masatoshi Hoshino2Tadao Tsujio3Akinobu Suzuki4Takashi Namikawa5Minori Kato6Akira Matsumura7Kazushi Takayama8Hiromitsu Toyoda9Koji Tamai10Shoichiro Ohyama11Yusuke Hori12Akito Yabu13Hiroaki Nakamura14 Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Shiraniwa Hospital, Shiraniwadai Ikoma City, Nara, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City General Hospital, Miyakojima-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City General Hospital, Miyakojima-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City General Hospital, Miyakojima-ku, Osaka, Japan Department of Orthopaedic Surgery, Seikeikai Hospital, Sakai City, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, JapanIntroduction: The presence of existing osteoporotic vertebral fracture (OVF) increases the mortality risk. However, the influence of the characteristics of OVF is unclear. This study aimed to investigate the influence of new OVF on patients’ long-term prognosis using our past cohort study. Method: This is an extension study of our cohort study carried out between 2005 and 2007. In the present extension study, of 420 patients, 197 whose contact information was available at the 6-month follow-up were included in the telephone survey in 2018. Five patients refused to participate in the survey, and 82 could not be contacted. Eventually, 110 patients were enrolled. Of the Demographic data, radiological findings, medical history, and clinical outcome were investigated at injury onset and at the 6-month follow-up. A proportional hazard model was used to investigate the risk factors for mortality. Results: Among 110 patients, 33 died. Male sex and low body mass index (BMI <18.5 kg/m 2 ) were significant risk factors for mortality [hazard ratio (HR) = 6.40, 1.01–40.50; 5.24, 1.44–19.04, respectively]. The history of stroke and liver disease increased the risk of mortality (HR = 13.37, 1.93–92.7; 6.62, 1.15–38.14, respectively). As regards radiological findings, local kyphosis progression per 1° or ≥7° were significant risk factors of mortality (HR = 1.20, 1.06–1.36; 5.38, 1.81–16.03, respectively). Conclusions: A telephone survey at 12 years after the occurrence of OVF analyzed risk factors for mortality and showed that a progression of local kyphosis in fractures between injury onset and 6 months after injury was a risk factor of poor prognosis.https://doi.org/10.1177/2309499021994969 |
| spellingShingle | Shinji Takahashi Hidetomi Terai Masatoshi Hoshino Tadao Tsujio Akinobu Suzuki Takashi Namikawa Minori Kato Akira Matsumura Kazushi Takayama Hiromitsu Toyoda Koji Tamai Shoichiro Ohyama Yusuke Hori Akito Yabu Hiroaki Nakamura Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study Journal of Orthopaedic Surgery |
| title | Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study |
| title_full | Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study |
| title_fullStr | Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study |
| title_full_unstemmed | Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study |
| title_short | Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study |
| title_sort | risk factors of the poor long term prognosis of osteoporotic vertebral fractures a multicenter cohort study |
| url | https://doi.org/10.1177/2309499021994969 |
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