Akkermansia Muciniphila Suppresses Non-alcoholic Steatohepatitis-associated Liver Cancer in Mice by Recovering Intestinal Barrier Function

Akkermansia Muciniphila Suppresses Non-alcoholic Steatohepatitis-associated Liver Cancer in Mice by Recovering Intestinal Barrier Function

Objective To investigate whether the next-generation probiotics Akkermansia muciniphila can prevent non-alcoholic steatohepatitis (NASH)-related hepatocellular carcinoma (HCC). Methods We constructed a NASH-HCC model called STAM. STAM mice received oral saline or A. muciniphila starting at 4 weeks o...

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Bibliographic Details
Main Authors: ZHANG Wujian, LI Tao
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2023-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
probiotics
akkermansia muciniphila
non-alcoholic fatty liver disease
hepatocellular carcinoma
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1259

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