Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study
Introduction: Acute traumatic coagulopathy (ATC) is defined as having evidence of coagulopathy in patients with severe trauma. The aim of this preliminary study was to assess the prevalence and associated factors of ATC in severely traumatic patients presenting to emergency department (ED). Method...
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2017-08-01
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| Series: | Archives of Academic Emergency Medicine |
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| Online Access: | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/183 |
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| author | Hojjat Derakhshanfar Ali Vafaei Ali Tabatabaey Shamila Noori |
| author_facet | Hojjat Derakhshanfar Ali Vafaei Ali Tabatabaey Shamila Noori |
| author_sort | Hojjat Derakhshanfar |
| collection | DOAJ |
| description | Introduction: Acute traumatic coagulopathy (ATC) is defined as having evidence of coagulopathy in patients with severe trauma. The aim of this preliminary study was to assess the prevalence and associated factors of ATC in severely traumatic patients presenting to emergency department (ED). Methods: In this retrospective cross sectional study, all patients with severe traumatic injury and available coagulation profile, presenting to the EDs of two major trauma centers in Tehran, Iran, during one year, were studied. Rate of ATC was determined and the associations with various variables as well as outcome were analyzed using SPSS 21. Results: 246 patients with the mean age of 36.57±17.11 years were included (88.2% male). The mean injury severity score (ISS) was 21.83 ± 7.37 (16 – 54). Patients were resuscitated with 676.83 ± 452.02 (0 – 1500) ml intravenous fluid before arriving at the ED. The maximum and minimum frequencies of ATC were 31.3% based on PTT > 36s and 2.4% based on PT > 18s, respectively. There was a significant association between the occurrence of ATC (PT ratio > 1.2) and ISS > 23 (p = 0.001), abdominal abbreviated injury score (AIS) > 3 (p = 0.003), base deficit > 4 (p = 0.019), pulse rate > 90/minute (p = 0.041), and pH < 7.30 (p = 0.043). Conclusion: The frequency of ATC in the present series varied from 2.4% to 31.3% based on different ATC definitions. Abdominal AIS > 3 and base deficit > 4 were among the significant independent factors related to ATC occurrence based on stepwise logistic regression analysis. |
| first_indexed | 2024-04-11T22:59:29Z |
| format | Article |
| id | doaj.art-70fb7f8e3c874536b0c9cc4fdac0d5b2 |
| institution | Directory Open Access Journal |
| issn | 2645-4904 |
| language | English |
| last_indexed | 2024-04-11T22:59:29Z |
| publishDate | 2017-08-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Archives of Academic Emergency Medicine |
| spelling | doaj.art-70fb7f8e3c874536b0c9cc4fdac0d5b22022-12-22T03:58:15ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042017-08-015110.22037/aaem.v5i1.183Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional StudyHojjat Derakhshanfar0Ali Vafaei1Ali Tabatabaey2Shamila Noori3Emergency Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Emergency Department, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Emergency Department, Shahid Beheshti Hospital, Qom University of Medical Sciences, Qom, Iran.Pathology Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Introduction: Acute traumatic coagulopathy (ATC) is defined as having evidence of coagulopathy in patients with severe trauma. The aim of this preliminary study was to assess the prevalence and associated factors of ATC in severely traumatic patients presenting to emergency department (ED). Methods: In this retrospective cross sectional study, all patients with severe traumatic injury and available coagulation profile, presenting to the EDs of two major trauma centers in Tehran, Iran, during one year, were studied. Rate of ATC was determined and the associations with various variables as well as outcome were analyzed using SPSS 21. Results: 246 patients with the mean age of 36.57±17.11 years were included (88.2% male). The mean injury severity score (ISS) was 21.83 ± 7.37 (16 – 54). Patients were resuscitated with 676.83 ± 452.02 (0 – 1500) ml intravenous fluid before arriving at the ED. The maximum and minimum frequencies of ATC were 31.3% based on PTT > 36s and 2.4% based on PT > 18s, respectively. There was a significant association between the occurrence of ATC (PT ratio > 1.2) and ISS > 23 (p = 0.001), abdominal abbreviated injury score (AIS) > 3 (p = 0.003), base deficit > 4 (p = 0.019), pulse rate > 90/minute (p = 0.041), and pH < 7.30 (p = 0.043). Conclusion: The frequency of ATC in the present series varied from 2.4% to 31.3% based on different ATC definitions. Abdominal AIS > 3 and base deficit > 4 were among the significant independent factors related to ATC occurrence based on stepwise logistic regression analysis.https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/183Blood coagulation disordersmultiple traumarisk factorsemergency servicehospitaloutcome assessment |
| spellingShingle | Hojjat Derakhshanfar Ali Vafaei Ali Tabatabaey Shamila Noori Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study Archives of Academic Emergency Medicine Blood coagulation disorders multiple trauma risk factors emergency service hospital outcome assessment |
| title | Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study |
| title_full | Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study |
| title_fullStr | Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study |
| title_full_unstemmed | Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study |
| title_short | Prevalence and Associated Factors of Acute Traumatic Coagulopathy; a Cross Sectional Study |
| title_sort | prevalence and associated factors of acute traumatic coagulopathy a cross sectional study |
| topic | Blood coagulation disorders multiple trauma risk factors emergency service hospital outcome assessment |
| url | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/183 |
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