Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease
Due to various causes, chronic kidney disease（CKD） is characterized by chronic irreversible changes in the structure and function of kidney. The most common pathological manifestation is renal fibrosis. Many studies have demonstrated that injured renal tubular epithelial cells could release a large...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2024-03-01
|
| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/cn/article/doi/10.3969/j.issn.1671-2390.2024.03.009 |
| _version_ | 1797237001471131648 |
|---|---|
| author | Chuan-ling Wang Shi-qiu Zhang Yan-wei Cao Ji Li Yong-jun Zhu |
| author_facet | Chuan-ling Wang Shi-qiu Zhang Yan-wei Cao Ji Li Yong-jun Zhu |
| author_sort | Chuan-ling Wang |
| collection | DOAJ |
| description | Due to various causes, chronic kidney disease（CKD） is characterized by chronic irreversible changes in the structure and function of kidney. The most common pathological manifestation is renal fibrosis. Many studies have demonstrated that injured renal tubular epithelial cells could release a large variety of cytokines to cause extracellular matrix deposition and promote the development of renal fibrosis during CKD. This review summarized the latest studies on the roles of renal tubular epithelial cell injury-related cytokines in CKD. It provided new concepts for clarifying the mechanism and exploring new treatments of CKD. |
| first_indexed | 2024-04-24T17:12:48Z |
| format | Article |
| id | doaj.art-70fc0db0c7a74afc9ecfb4e1b45c8498 |
| institution | Directory Open Access Journal |
| issn | 1671-2390 |
| language | zho |
| last_indexed | 2024-04-24T17:12:48Z |
| publishDate | 2024-03-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj.art-70fc0db0c7a74afc9ecfb4e1b45c84982024-03-28T09:00:08ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902024-03-0124323824310.3969/j.issn.1671-2390.2024.03.00920230161Roles of renal tubular epithelial cell injury related cytokines in chronic kidney diseaseChuan-ling Wang0Shi-qiu Zhang1Yan-wei Cao2Ji Li3Yong-jun Zhu4Department of Nephrology, First Affiliated Hospital, Hainan Medical University, Haikou 570102, ChinaDepartment of Nephrology, First Affiliated Hospital, Hainan Medical University, Haikou 570102, ChinaDepartment of Nephrology, First Affiliated Hospital, Hainan Medical University, Haikou 570102, ChinaDepartment of Nephrology, First Affiliated Hospital, Hainan Medical University, Haikou 570102, ChinaDepartment of Nephrology, First Affiliated Hospital, Hainan Medical University, Haikou 570102, ChinaDue to various causes, chronic kidney disease（CKD） is characterized by chronic irreversible changes in the structure and function of kidney. The most common pathological manifestation is renal fibrosis. Many studies have demonstrated that injured renal tubular epithelial cells could release a large variety of cytokines to cause extracellular matrix deposition and promote the development of renal fibrosis during CKD. This review summarized the latest studies on the roles of renal tubular epithelial cell injury-related cytokines in CKD. It provided new concepts for clarifying the mechanism and exploring new treatments of CKD.http://www.lcszb.com/cn/article/doi/10.3969/j.issn.1671-2390.2024.03.009renal tubular epithelial cellschronic kidney diseasesrenal fibrosis |
| spellingShingle | Chuan-ling Wang Shi-qiu Zhang Yan-wei Cao Ji Li Yong-jun Zhu Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease Linchuang shenzangbing zazhi renal tubular epithelial cells chronic kidney diseases renal fibrosis |
| title | Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| title_full | Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| title_fullStr | Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| title_full_unstemmed | Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| title_short | Roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| title_sort | roles of renal tubular epithelial cell injury related cytokines in chronic kidney disease |
| topic | renal tubular epithelial cells chronic kidney diseases renal fibrosis |
| url | http://www.lcszb.com/cn/article/doi/10.3969/j.issn.1671-2390.2024.03.009 |
| work_keys_str_mv | AT chuanlingwang rolesofrenaltubularepithelialcellinjuryrelatedcytokinesinchronickidneydisease AT shiqiuzhang rolesofrenaltubularepithelialcellinjuryrelatedcytokinesinchronickidneydisease AT yanweicao rolesofrenaltubularepithelialcellinjuryrelatedcytokinesinchronickidneydisease AT jili rolesofrenaltubularepithelialcellinjuryrelatedcytokinesinchronickidneydisease AT yongjunzhu rolesofrenaltubularepithelialcellinjuryrelatedcytokinesinchronickidneydisease |