An integrated model of the human cornea as a linear biaxial birefringent medium

Abstract A novel model of human corneal birefringence is presented. The cornea is treated as a homogeneous biaxial linear birefringent medium in which the values of the binormal axes angle and organization of the main refractive indices vary continuously from the apex to the limbus. In its central p...

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Main Authors: Marcelina Sobczak, Agnieszka Jóźwik, Piotr Kurzynowski
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-55800-4
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author Marcelina Sobczak
Agnieszka Jóźwik
Piotr Kurzynowski
author_facet Marcelina Sobczak
Agnieszka Jóźwik
Piotr Kurzynowski
author_sort Marcelina Sobczak
collection DOAJ
description Abstract A novel model of human corneal birefringence is presented. The cornea is treated as a homogeneous biaxial linear birefringent medium in which the values of the binormal axes angle and organization of the main refractive indices vary continuously from the apex to the limbus. In its central part, the angle between binormal axes is 35°, and para centrally, it smoothly increases to 83.7°. The values of the main refractive indices (n x, n y, n z) change, as well as their order, from n x < n z < n y to n z < n x < n y. The transition between these two states was described with a normal distribution (μ = 0.45, σ = 0.1). The presented model corresponds with the experimental results presented in the literature. To our knowledge, it is the first model that presents the anisotropic properties’ distributions of the entire cornea. The presented model facilitates a better understanding of the corneal birefringence phenomenon directly related to its lamellar structure.
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spelling doaj.art-70fc90a557aa494f8100aedb9fd7fcbd2024-03-05T18:45:51ZengNature PortfolioScientific Reports2045-23222024-03-0114111310.1038/s41598-024-55800-4An integrated model of the human cornea as a linear biaxial birefringent mediumMarcelina Sobczak0Agnieszka Jóźwik1Piotr Kurzynowski2Department of Optics and Photonics, Wroclaw University of Science and TechnologyDepartment of Optics and Photonics, Wroclaw University of Science and TechnologyDepartment of Optics and Photonics, Wroclaw University of Science and TechnologyAbstract A novel model of human corneal birefringence is presented. The cornea is treated as a homogeneous biaxial linear birefringent medium in which the values of the binormal axes angle and organization of the main refractive indices vary continuously from the apex to the limbus. In its central part, the angle between binormal axes is 35°, and para centrally, it smoothly increases to 83.7°. The values of the main refractive indices (n x, n y, n z) change, as well as their order, from n x < n z < n y to n z < n x < n y. The transition between these two states was described with a normal distribution (μ = 0.45, σ = 0.1). The presented model corresponds with the experimental results presented in the literature. To our knowledge, it is the first model that presents the anisotropic properties’ distributions of the entire cornea. The presented model facilitates a better understanding of the corneal birefringence phenomenon directly related to its lamellar structure.https://doi.org/10.1038/s41598-024-55800-4
spellingShingle Marcelina Sobczak
Agnieszka Jóźwik
Piotr Kurzynowski
An integrated model of the human cornea as a linear biaxial birefringent medium
Scientific Reports
title An integrated model of the human cornea as a linear biaxial birefringent medium
title_full An integrated model of the human cornea as a linear biaxial birefringent medium
title_fullStr An integrated model of the human cornea as a linear biaxial birefringent medium
title_full_unstemmed An integrated model of the human cornea as a linear biaxial birefringent medium
title_short An integrated model of the human cornea as a linear biaxial birefringent medium
title_sort integrated model of the human cornea as a linear biaxial birefringent medium
url https://doi.org/10.1038/s41598-024-55800-4
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