Normative data for TM electrocochleography measures
Objective: Establish normative data for tympanic electrocochleography (TM ECochG) parameters in normal hearing adults without Ménière's disease's (MD) symptoms. Describe TM ECochG variables that help to distinguish normal from MD ears. Material and methods: We enrolled 100 subjects (N = 20...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-06-01
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| Series: | Journal of Otology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1672293017300235 |
| _version_ | 1819210055635959808 |
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| author | Signe Schuster Grasel Roberto Miquelino de Oliveira Beck Ricardo Silva Chiabai Loureiro Amanda Costa Rossi Edigar Rezende de Almeida John Ferraro |
| author_facet | Signe Schuster Grasel Roberto Miquelino de Oliveira Beck Ricardo Silva Chiabai Loureiro Amanda Costa Rossi Edigar Rezende de Almeida John Ferraro |
| author_sort | Signe Schuster Grasel |
| collection | DOAJ |
| description | Objective: Establish normative data for tympanic electrocochleography (TM ECochG) parameters in normal hearing adults without Ménière's disease's (MD) symptoms. Describe TM ECochG variables that help to distinguish normal from MD ears.
Material and methods: We enrolled 100 subjects (N = 200 ears), 59 females, aged between 19 and 71 years from 09/2010 to 04/2014. Inclusion criteria: normal otomicroscopy, hearing thresholds ≤25 dB nHL from 250 to 4000 Hz, normal tympanogram, no symptoms of MD according to the AAO-HNS 1995 criteria and Gibson's score <7. We excluded subjects with dizziness, aural fullness or other symptoms of endolymphatic hydrops. The following parameters were analyzed: SP/AP amplitude ratio, SP/AP area ratio and the difference between AP latency with rarefaction and condensation stimuli.
Results: There was no significant difference between right and left ears (Intraclass correlation coefficient < 0.6). SP/AP amplitude ratio varied between 0.084 and 0.356 and SP/AP area ratio between 0.837 and 1.671 (percentiles 5 and 95). The AP latency difference to rarefaction and condensation clicks was between 0.0 and 0.333 ms.
Conclusion: Normative data for TM ECochG parameters were established in 100 normal hearing subjects without MD. These data can be used to distinguish normal from pathological findings and in follow-up of MD patients. |
| first_indexed | 2024-12-23T06:05:06Z |
| format | Article |
| id | doaj.art-7101d3b485e64540b852f436e180702f |
| institution | Directory Open Access Journal |
| issn | 1672-2930 |
| language | English |
| last_indexed | 2024-12-23T06:05:06Z |
| publishDate | 2017-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Otology |
| spelling | doaj.art-7101d3b485e64540b852f436e180702f2022-12-21T17:57:34ZengElsevierJournal of Otology1672-29302017-06-01122687310.1016/j.joto.2017.04.005Normative data for TM electrocochleography measuresSigne Schuster Grasel0Roberto Miquelino de Oliveira Beck1Ricardo Silva Chiabai Loureiro2Amanda Costa Rossi3Edigar Rezende de Almeida4John Ferraro5University of Sao Paulo School of Medicine, Dr. Eneas de Carvalho Aguiar, 255, sala 6173, Cerqueira César, Sao Paulo, SP CEP 05403-000, BrazilUniversity of Sao Paulo School of Medicine, Dr. Eneas de Carvalho Aguiar, 255, sala 6173, Cerqueira César, Sao Paulo, SP CEP 05403-000, BrazilUniversity of Sao Paulo School of Medicine, Dr. Eneas de Carvalho Aguiar, 255, sala 6173, Cerqueira César, Sao Paulo, SP CEP 05403-000, BrazilUniversity of Sao Paulo School of Medicine, Dr. Eneas de Carvalho Aguiar, 255, sala 6173, Cerqueira César, Sao Paulo, SP CEP 05403-000, BrazilUniversity of Sao Paulo School of Medicine, Dr. Eneas de Carvalho Aguiar, 255, sala 6173, Cerqueira César, Sao Paulo, SP CEP 05403-000, BrazilUniversity of Kansas Medical Center, Kansas City, KS 66160, USAObjective: Establish normative data for tympanic electrocochleography (TM ECochG) parameters in normal hearing adults without Ménière's disease's (MD) symptoms. Describe TM ECochG variables that help to distinguish normal from MD ears. Material and methods: We enrolled 100 subjects (N = 200 ears), 59 females, aged between 19 and 71 years from 09/2010 to 04/2014. Inclusion criteria: normal otomicroscopy, hearing thresholds ≤25 dB nHL from 250 to 4000 Hz, normal tympanogram, no symptoms of MD according to the AAO-HNS 1995 criteria and Gibson's score <7. We excluded subjects with dizziness, aural fullness or other symptoms of endolymphatic hydrops. The following parameters were analyzed: SP/AP amplitude ratio, SP/AP area ratio and the difference between AP latency with rarefaction and condensation stimuli. Results: There was no significant difference between right and left ears (Intraclass correlation coefficient < 0.6). SP/AP amplitude ratio varied between 0.084 and 0.356 and SP/AP area ratio between 0.837 and 1.671 (percentiles 5 and 95). The AP latency difference to rarefaction and condensation clicks was between 0.0 and 0.333 ms. Conclusion: Normative data for TM ECochG parameters were established in 100 normal hearing subjects without MD. These data can be used to distinguish normal from pathological findings and in follow-up of MD patients.http://www.sciencedirect.com/science/article/pii/S1672293017300235ElectrocochleographyMénière diseaseHearingDizzinessTinnitus |
| spellingShingle | Signe Schuster Grasel Roberto Miquelino de Oliveira Beck Ricardo Silva Chiabai Loureiro Amanda Costa Rossi Edigar Rezende de Almeida John Ferraro Normative data for TM electrocochleography measures Journal of Otology Electrocochleography Ménière disease Hearing Dizziness Tinnitus |
| title | Normative data for TM electrocochleography measures |
| title_full | Normative data for TM electrocochleography measures |
| title_fullStr | Normative data for TM electrocochleography measures |
| title_full_unstemmed | Normative data for TM electrocochleography measures |
| title_short | Normative data for TM electrocochleography measures |
| title_sort | normative data for tm electrocochleography measures |
| topic | Electrocochleography Ménière disease Hearing Dizziness Tinnitus |
| url | http://www.sciencedirect.com/science/article/pii/S1672293017300235 |
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