Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

Summary: Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays key roles in the replication cycle and is a critical serological marker. Here, we characterize essential biochemical properties of N and describe the utility of these insights in serological studi...

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Bibliographic Details
Main Authors: Chao Wu, Abraham J. Qavi, Asmaa Hachim, Niloufar Kavian, Aidan R. Cole, Austin B. Moyle, Nicole D. Wagner, Joyce Sweeney-Gibbons, Henry W. Rohrs, Michael L. Gross, J. S. Malik Peiris, Christopher F. Basler, Christopher W. Farnsworth, Sophie A. Valkenburg, Gaya K. Amarasinghe, Daisy W. Leung
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Human Specimen
Virology
Biophysics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221006490

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