Artificial Organelles: Reactions inside Protein–Polymer Supramolecular Assemblies

Reactions inside confined compartments at the nanoscale represent an essential step in the development of complex multifunctional systems to serve as molecular factories. In this respect, the biomimetic approach of combining biomolecules (proteins, enzymes, mimics) with synthetic membranes...

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Bibliographic Details
Main Authors: Martina Garni, Tomaž Einfalt, Mihai Lomora, Anja Car, Wolfgang Meier, Cornelia G. Palivan
Format: Article
Language:deu
Published: Swiss Chemical Society 2016-06-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/1785
Description
Summary:Reactions inside confined compartments at the nanoscale represent an essential step in the development of complex multifunctional systems to serve as molecular factories. In this respect, the biomimetic approach of combining biomolecules (proteins, enzymes, mimics) with synthetic membranes is an elegant way to create functional nanoreactors, or even simple artificial organelles, that function inside cells after uptake. Functionality is provided by the specificity of the biomolecule(s), whilst the synthetic compartment provides mechanical stability and robustness. The availability of a large variety of biomolecules and synthetic membranes allows the properties and functionality of these reaction spaces to be tailored and adjusted for building complex self-organized systems as the basis for molecular factories.
ISSN:0009-4293
2673-2424