Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial
Lijuan Zhou,1,2,* Dan Shi,2 Liyuan Zhang,2,* Qian Wang,2 Li Chen,2 Honglin Chen3 1Medical School, Nantong University, Nantong, People’s Republic of China; 2Nursing Department, Taizhou People’s Hospital, Taizhou, People’s Republic of China; 3School of Public Health, Nantong University...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-02-01
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| Series: | Patient Preference and Adherence |
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| Online Access: | https://www.dovepress.com/does-intradialytic-group-exercise-programme-influence-patient-reported-peer-reviewed-fulltext-article-PPA |
| _version_ | 1797900971414650880 |
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| author | Zhou L Shi D Zhang L Wang Q Chen L Chen H |
| author_facet | Zhou L Shi D Zhang L Wang Q Chen L Chen H |
| author_sort | Zhou L |
| collection | DOAJ |
| description | Lijuan Zhou,1,2,* Dan Shi,2 Liyuan Zhang,2,* Qian Wang,2 Li Chen,2 Honglin Chen3 1Medical School, Nantong University, Nantong, People’s Republic of China; 2Nursing Department, Taizhou People’s Hospital, Taizhou, People’s Republic of China; 3School of Public Health, Nantong University, Nantong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Honglin Chen, Email honglinyjs@126.comBackground: Maintenance hemodialysis(MHD) patients often suffer from fatigue and are recommended to undertake physical activities. The optimal format of exercise rehabilitation for MHD patients remains uncertain despite demonstrated health benefits. This study aimed to evaluate the effectiveness of an intradialytic group exercise programme for MHD patients.Methods: This was a single-centre, single-group repeated-measures design study. The 12-week, three times per-week intradialytic group exercise programme was conducted for around 30 min during the first 2 hours of each dialysis session. Patient-reported outcomes including fatigue, anxiety, depression and health-related quality of life, laboratory parameters including haemoglobin, albumin, pre-albumin and hypersensitive C-reactive protein, and anthropometric parameters including triceps skinfold thickness, mid-upper arm circumference, mid-arm muscle circumference and handgrip strength, were measured at baseline, immediately post-intervention and 12-weeks post-intervention. The repeated-measures analysis of variance and Friedman test were used to compare the parametric and non‐parametric data across time points, respectively.Results: Ninety patients were enrolled and 75 completed. Participants reported significant improvements across time points in fatigue (F = 10.19, p < 0.01), depression (F = 19.20, p < 0.001), health-related quality of life (F = 5.36, p = 0.006), haemoglobin (F = 3.43, p = 0.047), albumin (F = 4.42, p = 0.032), hypersensitive C-reactive protein (χ2 = 50.39, p < 0.001), pre-albumin (χ2 = 11.85, p = 0.003), triceps skinfold thickness (F = 25.03, p < 0.001), mid-upper arm circumference (F = 6.32, p = 0.005), mid-arm muscle circumference (F = 4.89, p = 0.02), and handgrip strength (F = 13.59, p < 0.001). Although the mean anxiety score tended to reduce, the difference across time points was nonsignificant (F = 1.33, p = 0.27).Conclusion: The findings suggested that the intradialytic group exercise programme could improve MHD patients’ fatigue, depression, health-related quality of life, nutritional status, and inflammation.Trial Registration: Chinese Clinical Trial Registry ChiCTR2000034394 (04/07/2020).Keywords: maintenance hemodialysis, group exercise, aerobic exercise, resistance exercise nutrition, quality of life |
| first_indexed | 2024-04-10T08:54:29Z |
| format | Article |
| id | doaj.art-7108640553e44e4ab68a9a5162d2f264 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-04-10T08:54:29Z |
| publishDate | 2023-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-7108640553e44e4ab68a9a5162d2f2642023-02-21T18:00:14ZengDove Medical PressPatient Preference and Adherence1177-889X2023-02-01Volume 1749150181798Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures TrialZhou LShi DZhang LWang QChen LChen HLijuan Zhou,1,2,* Dan Shi,2 Liyuan Zhang,2,* Qian Wang,2 Li Chen,2 Honglin Chen3 1Medical School, Nantong University, Nantong, People’s Republic of China; 2Nursing Department, Taizhou People’s Hospital, Taizhou, People’s Republic of China; 3School of Public Health, Nantong University, Nantong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Honglin Chen, Email honglinyjs@126.comBackground: Maintenance hemodialysis(MHD) patients often suffer from fatigue and are recommended to undertake physical activities. The optimal format of exercise rehabilitation for MHD patients remains uncertain despite demonstrated health benefits. This study aimed to evaluate the effectiveness of an intradialytic group exercise programme for MHD patients.Methods: This was a single-centre, single-group repeated-measures design study. The 12-week, three times per-week intradialytic group exercise programme was conducted for around 30 min during the first 2 hours of each dialysis session. Patient-reported outcomes including fatigue, anxiety, depression and health-related quality of life, laboratory parameters including haemoglobin, albumin, pre-albumin and hypersensitive C-reactive protein, and anthropometric parameters including triceps skinfold thickness, mid-upper arm circumference, mid-arm muscle circumference and handgrip strength, were measured at baseline, immediately post-intervention and 12-weeks post-intervention. The repeated-measures analysis of variance and Friedman test were used to compare the parametric and non‐parametric data across time points, respectively.Results: Ninety patients were enrolled and 75 completed. Participants reported significant improvements across time points in fatigue (F = 10.19, p < 0.01), depression (F = 19.20, p < 0.001), health-related quality of life (F = 5.36, p = 0.006), haemoglobin (F = 3.43, p = 0.047), albumin (F = 4.42, p = 0.032), hypersensitive C-reactive protein (χ2 = 50.39, p < 0.001), pre-albumin (χ2 = 11.85, p = 0.003), triceps skinfold thickness (F = 25.03, p < 0.001), mid-upper arm circumference (F = 6.32, p = 0.005), mid-arm muscle circumference (F = 4.89, p = 0.02), and handgrip strength (F = 13.59, p < 0.001). Although the mean anxiety score tended to reduce, the difference across time points was nonsignificant (F = 1.33, p = 0.27).Conclusion: The findings suggested that the intradialytic group exercise programme could improve MHD patients’ fatigue, depression, health-related quality of life, nutritional status, and inflammation.Trial Registration: Chinese Clinical Trial Registry ChiCTR2000034394 (04/07/2020).Keywords: maintenance hemodialysis, group exercise, aerobic exercise, resistance exercise nutrition, quality of lifehttps://www.dovepress.com/does-intradialytic-group-exercise-programme-influence-patient-reported-peer-reviewed-fulltext-article-PPAmaintenance hemodialysisgroup exerciseaerobic exerciseresistance exercise nutritionquality of life |
| spellingShingle | Zhou L Shi D Zhang L Wang Q Chen L Chen H Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial Patient Preference and Adherence maintenance hemodialysis group exercise aerobic exercise resistance exercise nutrition quality of life |
| title | Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial |
| title_full | Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial |
| title_fullStr | Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial |
| title_full_unstemmed | Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial |
| title_short | Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial |
| title_sort | does intradialytic group exercise programme influence patient reported outcomes laboratory parameters and anthropometric parameters in maintenance hemodialysis patients a single group repeated measures trial |
| topic | maintenance hemodialysis group exercise aerobic exercise resistance exercise nutrition quality of life |
| url | https://www.dovepress.com/does-intradialytic-group-exercise-programme-influence-patient-reported-peer-reviewed-fulltext-article-PPA |
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