Exosomal lncRNA LINC01356 Derived From Brain Metastatic Nonsmall-Cell Lung Cancer Cells Remodels the Blood–Brain Barrier

Exosomal lncRNA LINC01356 Derived From Brain Metastatic Nonsmall-Cell Lung Cancer Cells Remodels the Blood–Brain Barrier

Brain metastasis is a severe complication that affects the survival of lung cancer patients. However, the mechanism of brain metastasis in lung cancer remains unclear. In this study, we constructed an in vitro BBB model and found that cells from the high-metastatic nonsmall cell lung cancer (NSCLC)...

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Bibliographic Details
Main Authors: Sumin Geng, Shaohua Tu, Zhenwei Bai, Yixiong Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
lung cancer
lncRNA LINC01356
exosome
BBB
brain metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.825899/full

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