Post-fever retinitis – Newer concepts

Post-fever retinitis (PFR) is an infectious or para-infectious uveitic entity caused by bacterial or viral agents and seen mainly in tropical countries. Systemic symptoms such as joint pain, skin rash are common during the febrile stage. On the basis of only clinical presentation, it is difficult to...

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Main Authors: Padmamalini Mahendradas, Ankush Kawali, Saurabh Luthra, Sanjay Srinivasan, Andre L Curi, Shrey Maheswari, Imen Ksiaa, Moncef Khairallah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1775;epage=1786;aulast=Mahendradas
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author Padmamalini Mahendradas
Ankush Kawali
Saurabh Luthra
Sanjay Srinivasan
Andre L Curi
Shrey Maheswari
Imen Ksiaa
Moncef Khairallah
author_facet Padmamalini Mahendradas
Ankush Kawali
Saurabh Luthra
Sanjay Srinivasan
Andre L Curi
Shrey Maheswari
Imen Ksiaa
Moncef Khairallah
author_sort Padmamalini Mahendradas
collection DOAJ
description Post-fever retinitis (PFR) is an infectious or para-infectious uveitic entity caused by bacterial or viral agents and seen mainly in tropical countries. Systemic symptoms such as joint pain, skin rash are common during the febrile stage. On the basis of only clinical presentation, it is difficult to pin-point the exact etiology for PFR. Serological investigations, polymerase chain reaction, and knowledge of concurrent epidemics in the community may help to identify the etiological organism. Bacterial causes of PFR such as rickettsia and typhoid are treated with systemic antibiotics, with or without systemic steroid therapy, whereas PFR of viral causes such as chikungunya, dengue, West Nile virus, and Zika virus have no specific treatment and are managed with steroids. Nevertheless, many authors have advocated mere observation and the uveitis resolved with its natural course of the disease. In this article, we have discussed the clinical features, pathogenesis, investigations, and management of PFR.
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spelling doaj.art-710b8089721748caa658b538d08922e82022-12-22T02:06:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016891775178610.4103/ijo.IJO_1352_20Post-fever retinitis – Newer conceptsPadmamalini MahendradasAnkush KawaliSaurabh LuthraSanjay SrinivasanAndre L CuriShrey MaheswariImen KsiaaMoncef KhairallahPost-fever retinitis (PFR) is an infectious or para-infectious uveitic entity caused by bacterial or viral agents and seen mainly in tropical countries. Systemic symptoms such as joint pain, skin rash are common during the febrile stage. On the basis of only clinical presentation, it is difficult to pin-point the exact etiology for PFR. Serological investigations, polymerase chain reaction, and knowledge of concurrent epidemics in the community may help to identify the etiological organism. Bacterial causes of PFR such as rickettsia and typhoid are treated with systemic antibiotics, with or without systemic steroid therapy, whereas PFR of viral causes such as chikungunya, dengue, West Nile virus, and Zika virus have no specific treatment and are managed with steroids. Nevertheless, many authors have advocated mere observation and the uveitis resolved with its natural course of the disease. In this article, we have discussed the clinical features, pathogenesis, investigations, and management of PFR.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1775;epage=1786;aulast=Mahendradaschikungunyadenguepost-fever retinitisrickettsiasystemic steroidstyphoidwest nile viruszika virus
spellingShingle Padmamalini Mahendradas
Ankush Kawali
Saurabh Luthra
Sanjay Srinivasan
Andre L Curi
Shrey Maheswari
Imen Ksiaa
Moncef Khairallah
Post-fever retinitis – Newer concepts
Indian Journal of Ophthalmology
chikungunya
dengue
post-fever retinitis
rickettsia
systemic steroids
typhoid
west nile virus
zika virus
title Post-fever retinitis – Newer concepts
title_full Post-fever retinitis – Newer concepts
title_fullStr Post-fever retinitis – Newer concepts
title_full_unstemmed Post-fever retinitis – Newer concepts
title_short Post-fever retinitis – Newer concepts
title_sort post fever retinitis newer concepts
topic chikungunya
dengue
post-fever retinitis
rickettsia
systemic steroids
typhoid
west nile virus
zika virus
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1775;epage=1786;aulast=Mahendradas
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