NeuroCave: A web-based immersive visualization platform for exploring connectome datasets

We introduce NeuroCave, a novel immersive visualization system that facilitates the visual inspection of structural and functional connectome datasets. The representation of the human connectome as a graph enables neuroscientists to apply network-theoretic approaches in order to explore its complex...

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Main Authors: Johnson J. G. Keiriz, Liang Zhan, Olusola Ajilore, Alex D. Leow, Angus G. Forbes
Format: Article
Language:English
Published: The MIT Press 2018-09-01
Series:Network Neuroscience
Subjects:
Online Access:https://www.mitpressjournals.org/doi/pdf/10.1162/netn_a_00044
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author Johnson J. G. Keiriz
Liang Zhan
Olusola Ajilore
Alex D. Leow
Angus G. Forbes
author_facet Johnson J. G. Keiriz
Liang Zhan
Olusola Ajilore
Alex D. Leow
Angus G. Forbes
author_sort Johnson J. G. Keiriz
collection DOAJ
description We introduce NeuroCave, a novel immersive visualization system that facilitates the visual inspection of structural and functional connectome datasets. The representation of the human connectome as a graph enables neuroscientists to apply network-theoretic approaches in order to explore its complex characteristics. With NeuroCave, brain researchers can interact with the connectome—either in a standard desktop environment or while wearing portable virtual reality headsets (such as Oculus Rift, Samsung Gear, or Google Daydream VR platforms)—in any coordinate system or topological space, as well as cluster brain regions into different modules on-demand. Furthermore, a default side-by-side layout enables simultaneous, synchronized manipulation in 3D, utilizing modern GPU hardware architecture, and facilitates comparison tasks across different subjects or diagnostic groups or longitudinally within the same subject. Visual clutter is mitigated using a state-of-the-art edge bundling technique and through an interactive layout strategy, while modular structure is optimally positioned in 3D exploiting mathematical properties of platonic solids. NeuroCave provides new functionality to support a range of analysis tasks not available in other visualization software platforms. NeuroCave is a web-based software application that facilitates the exploration of and comparison between connectome datasets in virtual reality environments. This article describes the visualization features provided by NeuroCave, enabling clinical neuroscientists to investigate connectome datasets in a flexible manner, to detect patterns within connectome data, and to generate hypotheses about these observations. NeuroCave is open source software freely available via our GitHub code repository at https://github.com/CreativeCodingLab/NeuroCave.
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spelling doaj.art-710e2d5d976b4a3e87ad989f2bbaa3152022-12-21T18:13:31ZengThe MIT PressNetwork Neuroscience2472-17512018-09-012334436110.1162/netn_a_00044netn_a_00044NeuroCave: A web-based immersive visualization platform for exploring connectome datasetsJohnson J. G. Keiriz0Liang Zhan1Olusola Ajilore2Alex D. Leow3Angus G. Forbes4Department of Computer Science, University of Illinois at Chicago, Chicago, IL, USADepartment of Engineering and Technology, University of Wisconsin–Stout Menomonie, WI, USADepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USADepartment of Computer Science, University of Illinois at Chicago, Chicago, IL, USADepartment of Computer Science, University of Illinois at Chicago, Chicago, IL, USAWe introduce NeuroCave, a novel immersive visualization system that facilitates the visual inspection of structural and functional connectome datasets. The representation of the human connectome as a graph enables neuroscientists to apply network-theoretic approaches in order to explore its complex characteristics. With NeuroCave, brain researchers can interact with the connectome—either in a standard desktop environment or while wearing portable virtual reality headsets (such as Oculus Rift, Samsung Gear, or Google Daydream VR platforms)—in any coordinate system or topological space, as well as cluster brain regions into different modules on-demand. Furthermore, a default side-by-side layout enables simultaneous, synchronized manipulation in 3D, utilizing modern GPU hardware architecture, and facilitates comparison tasks across different subjects or diagnostic groups or longitudinally within the same subject. Visual clutter is mitigated using a state-of-the-art edge bundling technique and through an interactive layout strategy, while modular structure is optimally positioned in 3D exploiting mathematical properties of platonic solids. NeuroCave provides new functionality to support a range of analysis tasks not available in other visualization software platforms. NeuroCave is a web-based software application that facilitates the exploration of and comparison between connectome datasets in virtual reality environments. This article describes the visualization features provided by NeuroCave, enabling clinical neuroscientists to investigate connectome datasets in a flexible manner, to detect patterns within connectome data, and to generate hypotheses about these observations. NeuroCave is open source software freely available via our GitHub code repository at https://github.com/CreativeCodingLab/NeuroCave.https://www.mitpressjournals.org/doi/pdf/10.1162/netn_a_00044Connectome visualizationImmersive analyticsIntrinsic geometryNetwork analysis
spellingShingle Johnson J. G. Keiriz
Liang Zhan
Olusola Ajilore
Alex D. Leow
Angus G. Forbes
NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
Network Neuroscience
Connectome visualization
Immersive analytics
Intrinsic geometry
Network analysis
title NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
title_full NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
title_fullStr NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
title_full_unstemmed NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
title_short NeuroCave: A web-based immersive visualization platform for exploring connectome datasets
title_sort neurocave a web based immersive visualization platform for exploring connectome datasets
topic Connectome visualization
Immersive analytics
Intrinsic geometry
Network analysis
url https://www.mitpressjournals.org/doi/pdf/10.1162/netn_a_00044
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