Acute Pancreatitis: An Atypical Presentation

Acute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 cr...

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Main Authors: Omar Nadhem, Omar Salh
Format: Article
Language:English
Published: Karger Publishers 2017-05-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/475920
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author Omar Nadhem
Omar Salh
author_facet Omar Nadhem
Omar Salh
author_sort Omar Nadhem
collection DOAJ
description Acute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 criteria: (1) abdominal pain consistent with pancreatitis, (2) serum lipase and/or amylase ≥3 times the upper limit of normal, and (3) characteristic findings from abdominal imaging. The sensitivity and specificity of lipase in diagnosing acute pancreatitis are undisputed. However, normal lipase level should not exclude a pancreatitis diagnosis. In patients with atypical pancreatitis presentation, imaging is needed. We experienced two cases of acute pancreatitis associated with normal serum enzyme levels. Both patients were diagnosed based on clinical and radiological evidence. They were successfully treated with intravenous fluids and analgesics with clinical and laboratory improvement. The importance of this case series is the unlikely presentation of acute pancreatitis. We believe that more research is needed to determine the exact proportion of acute pancreatitis patients who first present with normal serum lipase, since similar cases have been seen in case reports.
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spelling doaj.art-710eae5c781b44adb6062cdc2df4de332022-12-22T01:12:55ZengKarger PublishersCase Reports in Gastroenterology1662-06312017-05-0111235936310.1159/000475920475920Acute Pancreatitis: An Atypical PresentationOmar NadhemOmar SalhAcute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 criteria: (1) abdominal pain consistent with pancreatitis, (2) serum lipase and/or amylase ≥3 times the upper limit of normal, and (3) characteristic findings from abdominal imaging. The sensitivity and specificity of lipase in diagnosing acute pancreatitis are undisputed. However, normal lipase level should not exclude a pancreatitis diagnosis. In patients with atypical pancreatitis presentation, imaging is needed. We experienced two cases of acute pancreatitis associated with normal serum enzyme levels. Both patients were diagnosed based on clinical and radiological evidence. They were successfully treated with intravenous fluids and analgesics with clinical and laboratory improvement. The importance of this case series is the unlikely presentation of acute pancreatitis. We believe that more research is needed to determine the exact proportion of acute pancreatitis patients who first present with normal serum lipase, since similar cases have been seen in case reports.http://www.karger.com/Article/FullText/475920Acute pancreatitisLipaseAmylaseAbdominal pain
spellingShingle Omar Nadhem
Omar Salh
Acute Pancreatitis: An Atypical Presentation
Case Reports in Gastroenterology
Acute pancreatitis
Lipase
Amylase
Abdominal pain
title Acute Pancreatitis: An Atypical Presentation
title_full Acute Pancreatitis: An Atypical Presentation
title_fullStr Acute Pancreatitis: An Atypical Presentation
title_full_unstemmed Acute Pancreatitis: An Atypical Presentation
title_short Acute Pancreatitis: An Atypical Presentation
title_sort acute pancreatitis an atypical presentation
topic Acute pancreatitis
Lipase
Amylase
Abdominal pain
url http://www.karger.com/Article/FullText/475920
work_keys_str_mv AT omarnadhem acutepancreatitisanatypicalpresentation
AT omarsalh acutepancreatitisanatypicalpresentation