Acute Pancreatitis: An Atypical Presentation
Acute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 cr...
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Format: | Article |
Language: | English |
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Karger Publishers
2017-05-01
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Series: | Case Reports in Gastroenterology |
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Online Access: | http://www.karger.com/Article/FullText/475920 |
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author | Omar Nadhem Omar Salh |
author_facet | Omar Nadhem Omar Salh |
author_sort | Omar Nadhem |
collection | DOAJ |
description | Acute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 criteria: (1) abdominal pain consistent with pancreatitis, (2) serum lipase and/or amylase ≥3 times the upper limit of normal, and (3) characteristic findings from abdominal imaging. The sensitivity and specificity of lipase in diagnosing acute pancreatitis are undisputed. However, normal lipase level should not exclude a pancreatitis diagnosis. In patients with atypical pancreatitis presentation, imaging is needed. We experienced two cases of acute pancreatitis associated with normal serum enzyme levels. Both patients were diagnosed based on clinical and radiological evidence. They were successfully treated with intravenous fluids and analgesics with clinical and laboratory improvement. The importance of this case series is the unlikely presentation of acute pancreatitis. We believe that more research is needed to determine the exact proportion of acute pancreatitis patients who first present with normal serum lipase, since similar cases have been seen in case reports. |
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id | doaj.art-710eae5c781b44adb6062cdc2df4de33 |
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issn | 1662-0631 |
language | English |
last_indexed | 2024-12-11T09:34:04Z |
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spelling | doaj.art-710eae5c781b44adb6062cdc2df4de332022-12-22T01:12:55ZengKarger PublishersCase Reports in Gastroenterology1662-06312017-05-0111235936310.1159/000475920475920Acute Pancreatitis: An Atypical PresentationOmar NadhemOmar SalhAcute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 criteria: (1) abdominal pain consistent with pancreatitis, (2) serum lipase and/or amylase ≥3 times the upper limit of normal, and (3) characteristic findings from abdominal imaging. The sensitivity and specificity of lipase in diagnosing acute pancreatitis are undisputed. However, normal lipase level should not exclude a pancreatitis diagnosis. In patients with atypical pancreatitis presentation, imaging is needed. We experienced two cases of acute pancreatitis associated with normal serum enzyme levels. Both patients were diagnosed based on clinical and radiological evidence. They were successfully treated with intravenous fluids and analgesics with clinical and laboratory improvement. The importance of this case series is the unlikely presentation of acute pancreatitis. We believe that more research is needed to determine the exact proportion of acute pancreatitis patients who first present with normal serum lipase, since similar cases have been seen in case reports.http://www.karger.com/Article/FullText/475920Acute pancreatitisLipaseAmylaseAbdominal pain |
spellingShingle | Omar Nadhem Omar Salh Acute Pancreatitis: An Atypical Presentation Case Reports in Gastroenterology Acute pancreatitis Lipase Amylase Abdominal pain |
title | Acute Pancreatitis: An Atypical Presentation |
title_full | Acute Pancreatitis: An Atypical Presentation |
title_fullStr | Acute Pancreatitis: An Atypical Presentation |
title_full_unstemmed | Acute Pancreatitis: An Atypical Presentation |
title_short | Acute Pancreatitis: An Atypical Presentation |
title_sort | acute pancreatitis an atypical presentation |
topic | Acute pancreatitis Lipase Amylase Abdominal pain |
url | http://www.karger.com/Article/FullText/475920 |
work_keys_str_mv | AT omarnadhem acutepancreatitisanatypicalpresentation AT omarsalh acutepancreatitisanatypicalpresentation |