A review of behavioral visual acuity tests for rodents
Rodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2018-04-01
|
Series: | Guoji Yanke Zazhi |
Subjects: | |
Online Access: | http://ies.ijo.cn/cn_publish/2018/4/201804012.pdf |
_version_ | 1819264610672312320 |
---|---|
author | Xiu-Yan Zhang Ai-Ling Bi Mei-Xia Zhan Peng Li Yue-Ying Zhang Xian-Zhen Ma Hong-Sheng Bi |
author_facet | Xiu-Yan Zhang Ai-Ling Bi Mei-Xia Zhan Peng Li Yue-Ying Zhang Xian-Zhen Ma Hong-Sheng Bi |
author_sort | Xiu-Yan Zhang |
collection | DOAJ |
description | Rodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have their advantages and limitations. The electrophysiology test(visual evoked potential)is invasive, and animals need recovery time after being implanted with electrodes. Also, the electrophysiological visual acuity test only reflects the electrical activity of a single cell or nuclei, it does not reflect the overall visual function of the animal. The widely used behavioral visual acuity test is able to compensate for these limitations. This paper gives a brief overview of the methods of the behavioral visual acuity test for rodents(rats, mice, guinea pigs, etc.). |
first_indexed | 2024-12-23T20:32:13Z |
format | Article |
id | doaj.art-71153488e1ce4a088037ef486df0d8c8 |
institution | Directory Open Access Journal |
issn | 1672-5123 1672-5123 |
language | English |
last_indexed | 2024-12-23T20:32:13Z |
publishDate | 2018-04-01 |
publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
record_format | Article |
series | Guoji Yanke Zazhi |
spelling | doaj.art-71153488e1ce4a088037ef486df0d8c82022-12-21T17:32:11ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-04-0118464564810.3980/j.issn.1672-5123.2018.4.12A review of behavioral visual acuity tests for rodentsXiu-Yan Zhang0Ai-Ling Bi1Mei-Xia Zhan2Peng Li3Yue-Ying Zhang4Xian-Zhen Ma5Hong-Sheng Bi6Ophthalmology and Optometry Medical School, Shandong University of Traditional Chinese Medicine, Jinan 250014,Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular DiseasesShandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular DiseasesLaboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaLaboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, ChinaShandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases; Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of ShandongOphthalmology and Optometry Medical School, Shandong University of Traditional Chinese Medicine, Jinan 250014,Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases; Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaRodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have their advantages and limitations. The electrophysiology test(visual evoked potential)is invasive, and animals need recovery time after being implanted with electrodes. Also, the electrophysiological visual acuity test only reflects the electrical activity of a single cell or nuclei, it does not reflect the overall visual function of the animal. The widely used behavioral visual acuity test is able to compensate for these limitations. This paper gives a brief overview of the methods of the behavioral visual acuity test for rodents(rats, mice, guinea pigs, etc.).http://ies.ijo.cn/cn_publish/2018/4/201804012.pdfrodentsbehavioral visual acuityvisual water taskvirtual optokinetic systemvirtual optokinetic system |
spellingShingle | Xiu-Yan Zhang Ai-Ling Bi Mei-Xia Zhan Peng Li Yue-Ying Zhang Xian-Zhen Ma Hong-Sheng Bi A review of behavioral visual acuity tests for rodents Guoji Yanke Zazhi rodents behavioral visual acuity visual water task virtual optokinetic system virtual optokinetic system |
title | A review of behavioral visual acuity tests for rodents |
title_full | A review of behavioral visual acuity tests for rodents |
title_fullStr | A review of behavioral visual acuity tests for rodents |
title_full_unstemmed | A review of behavioral visual acuity tests for rodents |
title_short | A review of behavioral visual acuity tests for rodents |
title_sort | review of behavioral visual acuity tests for rodents |
topic | rodents behavioral visual acuity visual water task virtual optokinetic system virtual optokinetic system |
url | http://ies.ijo.cn/cn_publish/2018/4/201804012.pdf |
work_keys_str_mv | AT xiuyanzhang areviewofbehavioralvisualacuitytestsforrodents AT ailingbi areviewofbehavioralvisualacuitytestsforrodents AT meixiazhan areviewofbehavioralvisualacuitytestsforrodents AT pengli areviewofbehavioralvisualacuitytestsforrodents AT yueyingzhang areviewofbehavioralvisualacuitytestsforrodents AT xianzhenma areviewofbehavioralvisualacuitytestsforrodents AT hongshengbi areviewofbehavioralvisualacuitytestsforrodents AT xiuyanzhang reviewofbehavioralvisualacuitytestsforrodents AT ailingbi reviewofbehavioralvisualacuitytestsforrodents AT meixiazhan reviewofbehavioralvisualacuitytestsforrodents AT pengli reviewofbehavioralvisualacuitytestsforrodents AT yueyingzhang reviewofbehavioralvisualacuitytestsforrodents AT xianzhenma reviewofbehavioralvisualacuitytestsforrodents AT hongshengbi reviewofbehavioralvisualacuitytestsforrodents |