A review of behavioral visual acuity tests for rodents

Rodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have...

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Main Authors: Xiu-Yan Zhang, Ai-Ling Bi, Mei-Xia Zhan, Peng Li, Yue-Ying Zhang, Xian-Zhen Ma, Hong-Sheng Bi
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-04-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2018/4/201804012.pdf
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author Xiu-Yan Zhang
Ai-Ling Bi
Mei-Xia Zhan
Peng Li
Yue-Ying Zhang
Xian-Zhen Ma
Hong-Sheng Bi
author_facet Xiu-Yan Zhang
Ai-Ling Bi
Mei-Xia Zhan
Peng Li
Yue-Ying Zhang
Xian-Zhen Ma
Hong-Sheng Bi
author_sort Xiu-Yan Zhang
collection DOAJ
description Rodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have their advantages and limitations. The electrophysiology test(visual evoked potential)is invasive, and animals need recovery time after being implanted with electrodes. Also, the electrophysiological visual acuity test only reflects the electrical activity of a single cell or nuclei, it does not reflect the overall visual function of the animal. The widely used behavioral visual acuity test is able to compensate for these limitations. This paper gives a brief overview of the methods of the behavioral visual acuity test for rodents(rats, mice, guinea pigs, etc.).
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spelling doaj.art-71153488e1ce4a088037ef486df0d8c82022-12-21T17:32:11ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-04-0118464564810.3980/j.issn.1672-5123.2018.4.12A review of behavioral visual acuity tests for rodentsXiu-Yan Zhang0Ai-Ling Bi1Mei-Xia Zhan2Peng Li3Yue-Ying Zhang4Xian-Zhen Ma5Hong-Sheng Bi6Ophthalmology and Optometry Medical School, Shandong University of Traditional Chinese Medicine, Jinan 250014,Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular DiseasesShandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular DiseasesLaboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaLaboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, ChinaShandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases; Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of ShandongOphthalmology and Optometry Medical School, Shandong University of Traditional Chinese Medicine, Jinan 250014,Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases; Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong; Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002,Shandong Province, ChinaRodents have been used widely in the research of eye diseases to study visual function in animal models. Two methods of visual acuity testing in animals have been internationally recognized: the electrophysiological visual acuity test and the behavioral visual acuity test. Both of these methods have their advantages and limitations. The electrophysiology test(visual evoked potential)is invasive, and animals need recovery time after being implanted with electrodes. Also, the electrophysiological visual acuity test only reflects the electrical activity of a single cell or nuclei, it does not reflect the overall visual function of the animal. The widely used behavioral visual acuity test is able to compensate for these limitations. This paper gives a brief overview of the methods of the behavioral visual acuity test for rodents(rats, mice, guinea pigs, etc.).http://ies.ijo.cn/cn_publish/2018/4/201804012.pdfrodentsbehavioral visual acuityvisual water taskvirtual optokinetic systemvirtual optokinetic system
spellingShingle Xiu-Yan Zhang
Ai-Ling Bi
Mei-Xia Zhan
Peng Li
Yue-Ying Zhang
Xian-Zhen Ma
Hong-Sheng Bi
A review of behavioral visual acuity tests for rodents
Guoji Yanke Zazhi
rodents
behavioral visual acuity
visual water task
virtual optokinetic system
virtual optokinetic system
title A review of behavioral visual acuity tests for rodents
title_full A review of behavioral visual acuity tests for rodents
title_fullStr A review of behavioral visual acuity tests for rodents
title_full_unstemmed A review of behavioral visual acuity tests for rodents
title_short A review of behavioral visual acuity tests for rodents
title_sort review of behavioral visual acuity tests for rodents
topic rodents
behavioral visual acuity
visual water task
virtual optokinetic system
virtual optokinetic system
url http://ies.ijo.cn/cn_publish/2018/4/201804012.pdf
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