Clinical and Histopathological Features of Scleroderma-like Disorders: An Update

Scleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical–pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud’s phenomenon and capillaroscop...

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Main Authors: Rosario Foti, Rocco De Pasquale, Ylenia Dal Bosco, Elisa Visalli, Giorgio Amato, Pietro Gangemi, Riccardo Foti, Alice Ramondetta
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/57/11/1275
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author Rosario Foti
Rocco De Pasquale
Ylenia Dal Bosco
Elisa Visalli
Giorgio Amato
Pietro Gangemi
Riccardo Foti
Alice Ramondetta
author_facet Rosario Foti
Rocco De Pasquale
Ylenia Dal Bosco
Elisa Visalli
Giorgio Amato
Pietro Gangemi
Riccardo Foti
Alice Ramondetta
author_sort Rosario Foti
collection DOAJ
description Scleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical–pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud’s phenomenon and capillaroscopic anomalies constitutes an important element of differential diagnosis with systemic sclerosis. When scleroderma can be excluded, on the basis of the main body sites, clinical evolution, any associated pathological conditions and specific histological features, it is possible to make a correct diagnosis.
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spelling doaj.art-711ca30efab048ec8538a1c243f75fbe2023-11-23T00:18:23ZengMDPI AGMedicina1010-660X1648-91442021-11-015711127510.3390/medicina57111275Clinical and Histopathological Features of Scleroderma-like Disorders: An UpdateRosario Foti0Rocco De Pasquale1Ylenia Dal Bosco2Elisa Visalli3Giorgio Amato4Pietro Gangemi5Riccardo Foti6Alice Ramondetta7Division of Reumathology, A.O.U. “Policlinico-San Marco”, 95123 Catania, ItalyU.O. Dermatologia, Ospedale San Marco, 95123 Catania, ItalyDivision of Reumathology, A.O.U. “Policlinico-San Marco”, 95123 Catania, ItalyDivision of Reumathology, A.O.U. “Policlinico-San Marco”, 95123 Catania, ItalyDivision of Reumathology, A.O.U. “Policlinico-San Marco”, 95123 Catania, ItalyU.O. Anatomia Patologica, Ospedale San Marco, 95123 Catania, ItalyU.O. Dermatologia, Ospedale San Marco, 95123 Catania, ItalyU.O. Dermatologia, Ospedale San Marco, 95123 Catania, ItalyScleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical–pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud’s phenomenon and capillaroscopic anomalies constitutes an important element of differential diagnosis with systemic sclerosis. When scleroderma can be excluded, on the basis of the main body sites, clinical evolution, any associated pathological conditions and specific histological features, it is possible to make a correct diagnosis.https://www.mdpi.com/1648-9144/57/11/1275scleroderma-likesclerodermiform mucinosisscleredemacutaneous sclerosis
spellingShingle Rosario Foti
Rocco De Pasquale
Ylenia Dal Bosco
Elisa Visalli
Giorgio Amato
Pietro Gangemi
Riccardo Foti
Alice Ramondetta
Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
Medicina
scleroderma-like
sclerodermiform mucinosis
scleredema
cutaneous sclerosis
title Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
title_full Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
title_fullStr Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
title_full_unstemmed Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
title_short Clinical and Histopathological Features of Scleroderma-like Disorders: An Update
title_sort clinical and histopathological features of scleroderma like disorders an update
topic scleroderma-like
sclerodermiform mucinosis
scleredema
cutaneous sclerosis
url https://www.mdpi.com/1648-9144/57/11/1275
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AT roccodepasquale clinicalandhistopathologicalfeaturesofsclerodermalikedisordersanupdate
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AT elisavisalli clinicalandhistopathologicalfeaturesofsclerodermalikedisordersanupdate
AT giorgioamato clinicalandhistopathologicalfeaturesofsclerodermalikedisordersanupdate
AT pietrogangemi clinicalandhistopathologicalfeaturesofsclerodermalikedisordersanupdate
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