Down-weighting overlapping genes improves gene set analysis

Down-weighting overlapping genes improves gene set analysis

<p>Abstract</p> <p>Background</p> <p>The identification of gene sets that are significantly impacted in a given condition based on microarray data is a crucial step in current life science research. Most gene set analysis methods treat genes equally, regardless how spec...

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Bibliographic Details
Main Authors: Tarca Adi, Draghici Sorin, Bhatti Gaurav, Romero Roberto
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Bioinformatics
Subjects:
Gene expression
Gene set analysis
Pathway analysis
Overlapping gene sets
Online Access:http://www.biomedcentral.com/1471-2105/13/136

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