A case of H. pylori infection presenting as refractory hypothyroidism
We present the case of a 45-year-old lady with long standing hypothyroidism who was euthyroid on replacement for many years, but stopped responding even to supraphysiological doses of LT4 since the last five years. She complained of abdominal discomfort, bloating, and nausea. She did not have diarrh...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=7;spage=3770;epage=3772;aulast=Gupta |
| _version_ | 1828341234469437440 |
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| author | Pragya Gupta Johns T Johnson Sudarsanababu Lalitha Soumya Kripa Elizabeth Cherian Nitin Kapoor Thomas Vizhalil Paul |
| author_facet | Pragya Gupta Johns T Johnson Sudarsanababu Lalitha Soumya Kripa Elizabeth Cherian Nitin Kapoor Thomas Vizhalil Paul |
| author_sort | Pragya Gupta |
| collection | DOAJ |
| description | We present the case of a 45-year-old lady with long standing hypothyroidism who was euthyroid on replacement for many years, but stopped responding even to supraphysiological doses of LT4 since the last five years. She complained of abdominal discomfort, bloating, and nausea. She did not have diarrhea or weight loss. Levothyroxine absorption test was done which was suggestive of malabsorption and she was started on triple therapy for H. pylori eradication after confirmation of diagnosis. After 10 days of treatment initiation, she developed symptoms of thyrotoxicosis with her supraphysiological dose of LT4, which was then tapered to a lower dose. Euthyroid state was ultimately achieved with lower doses of LT4 replacement. |
| first_indexed | 2024-04-13T23:10:50Z |
| format | Article |
| id | doaj.art-71216791a3d94e2ebebee9a3652fcff9 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-13T23:10:50Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-71216791a3d94e2ebebee9a3652fcff92022-12-22T02:25:35ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632020-01-01973770377210.4103/jfmpc.jfmpc_729_20A case of H. pylori infection presenting as refractory hypothyroidismPragya GuptaJohns T JohnsonSudarsanababu Lalitha SoumyaKripa Elizabeth CherianNitin KapoorThomas Vizhalil PaulWe present the case of a 45-year-old lady with long standing hypothyroidism who was euthyroid on replacement for many years, but stopped responding even to supraphysiological doses of LT4 since the last five years. She complained of abdominal discomfort, bloating, and nausea. She did not have diarrhea or weight loss. Levothyroxine absorption test was done which was suggestive of malabsorption and she was started on triple therapy for H. pylori eradication after confirmation of diagnosis. After 10 days of treatment initiation, she developed symptoms of thyrotoxicosis with her supraphysiological dose of LT4, which was then tapered to a lower dose. Euthyroid state was ultimately achieved with lower doses of LT4 replacement.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=7;spage=3770;epage=3772;aulast=Guptah. pylori infectionlevothyroxine absorption testrefractory hypothyroidism |
| spellingShingle | Pragya Gupta Johns T Johnson Sudarsanababu Lalitha Soumya Kripa Elizabeth Cherian Nitin Kapoor Thomas Vizhalil Paul A case of H. pylori infection presenting as refractory hypothyroidism Journal of Family Medicine and Primary Care h. pylori infection levothyroxine absorption test refractory hypothyroidism |
| title | A case of H. pylori infection presenting as refractory hypothyroidism |
| title_full | A case of H. pylori infection presenting as refractory hypothyroidism |
| title_fullStr | A case of H. pylori infection presenting as refractory hypothyroidism |
| title_full_unstemmed | A case of H. pylori infection presenting as refractory hypothyroidism |
| title_short | A case of H. pylori infection presenting as refractory hypothyroidism |
| title_sort | case of h pylori infection presenting as refractory hypothyroidism |
| topic | h. pylori infection levothyroxine absorption test refractory hypothyroidism |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=7;spage=3770;epage=3772;aulast=Gupta |
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