Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site

Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site

ABSTRACTThe mutations in the SARS-CoV-2 virus genome during COVID-19 dissemination are unclear. In 788 COVID-19 patients from Zhejiang province, we observed decreased rate of severe/critical cases compared with patients in Wuhan. For mechanisms exploration, we isolated one strain of SARS-CoV-2 (ZJ01...

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Bibliographic Details
Main Authors: Xi Jin, Kangli Xu, Penglei Jiang, Jiangshan Lian, Shaorui Hao, Hangping Yao, Hongyu Jia, Yimin Zhang, Lin Zheng, Nuoheng Zheng, Dong Chen, Jinmei Yao, Jianhua Hu, Jianguo Gao, Liang Wen, Jian Shen, Yue Ren, Guodong Yu, Xiaoyan Wang, Yingfeng Lu, Xiaopeng Yu, Liang Yu, Dairong Xiang, Nanping Wu, Xiangyun Lu, Linfang Cheng, Fumin Liu, Haibo Wu, Changzhong Jin, Xiaofeng Yang, Pengxu Qian, Yunqing Qiu, Jifang Sheng, Tingbo Liang, Lanjuan Li, Yida Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
COVID-19
Furin
ACE2
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1781551

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