Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: opportunities, challenges, and future development

Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: opportunities, challenges, and future development

Hypoxia, a salient feature of most solid tumors, confers invasiveness and resistance to the tumor cells. Oxygen-consumption photodynamic therapy (PDT) suffers from the undesirable impediment of local hypoxia in tumors. Moreover, PDT could further worsen hypoxia. Therefore, developing effective strat...

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Bibliographic Details
Main Authors: Yixin Sun, Dongyang Zhao, Gang Wang, Yang Wang, Linlin Cao, Jin Sun, Qikun Jiang, Zhonggui He
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Hypoxia
Photodynamic therapy
Cancer
Nanomedicine delivery systems
Oxygen
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519313735

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