Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China
Abstract Objective This study investigated the distribution of acquired antibiotic resistance genes in Enterococcus species isolated from clinical patients in Baotou, China. Result A total of 73 enterococca lisolates from clinical samples were collected from December 2016 to September 2017. Of the 7...
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| Format: | Article |
| Language: | English |
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BMC
2019-01-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-019-4064-z |
| _version_ | 1828176266746920960 |
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| author | Yingjie Tian Hui Yu Zhanli Wang |
| author_facet | Yingjie Tian Hui Yu Zhanli Wang |
| author_sort | Yingjie Tian |
| collection | DOAJ |
| description | Abstract Objective This study investigated the distribution of acquired antibiotic resistance genes in Enterococcus species isolated from clinical patients in Baotou, China. Result A total of 73 enterococca lisolates from clinical samples were collected from December 2016 to September 2017. Of the 73 enterococcal isolates, 36 (49.3%), 35 (47.9%), 1 (1.4%), and 1 (1.4%) were identified as E. faecium, E. faecalis, E. gallinarum, and E. raffinosus, respectively. The resistance rates of the enterococci to nitrofurantoin, tetracycline, gentamicin (high-level), ampicillin, ciprofloxacin and erythromycin were 24.7%, 49.3%, 50.7%, 54.8%, 74.0% and 89.0%, respectively. The most prevalent aminoglycoside resistance genes were aac(6′)-Ie-aph(2″)-Ia (64.9%) and aph(3′)IIIa (64.9%). The most common erythromycin ribosome methylation gene was erm(B) (67.7%), followed by erm(A) (4.6%) and erm(C) (1.5%). The tetracycline resistance gene tetM was found to be present in 100.0% of the tetracycline-resistant strains of enterococci. Thus, E. faecium and E. faecalis were identified as the species of greatest clinical importance associated with hospital-acquired enterococcal infections in Baotou, China. The antimicrobial resistance genes aac(6′)-Ie-aph(2″)-Ia, aph(3′)IIIa, tetM, and erm(B) were significantly more prevalent among the enterococcal isolates. Therefore, action should be taken to monitor drug resistance and antimicrobial resistance genes to manage multi-drug-resistant enterococcal infections. |
| first_indexed | 2024-04-12T04:41:18Z |
| format | Article |
| id | doaj.art-712fa54a1a47456f8e9b999f64ccb118 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-12T04:41:18Z |
| publishDate | 2019-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-712fa54a1a47456f8e9b999f64ccb1182022-12-22T03:47:38ZengBMCBMC Research Notes1756-05002019-01-011211510.1186/s13104-019-4064-zDistribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, ChinaYingjie Tian0Hui Yu1Zhanli Wang2The Second Affiliated Hospital, Baotou Medical CollegeThe Second Affiliated Hospital, Baotou Medical CollegeThe Second Affiliated Hospital, Baotou Medical CollegeAbstract Objective This study investigated the distribution of acquired antibiotic resistance genes in Enterococcus species isolated from clinical patients in Baotou, China. Result A total of 73 enterococca lisolates from clinical samples were collected from December 2016 to September 2017. Of the 73 enterococcal isolates, 36 (49.3%), 35 (47.9%), 1 (1.4%), and 1 (1.4%) were identified as E. faecium, E. faecalis, E. gallinarum, and E. raffinosus, respectively. The resistance rates of the enterococci to nitrofurantoin, tetracycline, gentamicin (high-level), ampicillin, ciprofloxacin and erythromycin were 24.7%, 49.3%, 50.7%, 54.8%, 74.0% and 89.0%, respectively. The most prevalent aminoglycoside resistance genes were aac(6′)-Ie-aph(2″)-Ia (64.9%) and aph(3′)IIIa (64.9%). The most common erythromycin ribosome methylation gene was erm(B) (67.7%), followed by erm(A) (4.6%) and erm(C) (1.5%). The tetracycline resistance gene tetM was found to be present in 100.0% of the tetracycline-resistant strains of enterococci. Thus, E. faecium and E. faecalis were identified as the species of greatest clinical importance associated with hospital-acquired enterococcal infections in Baotou, China. The antimicrobial resistance genes aac(6′)-Ie-aph(2″)-Ia, aph(3′)IIIa, tetM, and erm(B) were significantly more prevalent among the enterococcal isolates. Therefore, action should be taken to monitor drug resistance and antimicrobial resistance genes to manage multi-drug-resistant enterococcal infections.http://link.springer.com/article/10.1186/s13104-019-4064-zEnterococcusDrug resistanceAntibiotic resistance geneInfection |
| spellingShingle | Yingjie Tian Hui Yu Zhanli Wang Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China BMC Research Notes Enterococcus Drug resistance Antibiotic resistance gene Infection |
| title | Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China |
| title_full | Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China |
| title_fullStr | Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China |
| title_full_unstemmed | Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China |
| title_short | Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China |
| title_sort | distribution of acquired antibiotic resistance genes among enterococcus spp isolated from a hospital in baotou china |
| topic | Enterococcus Drug resistance Antibiotic resistance gene Infection |
| url | http://link.springer.com/article/10.1186/s13104-019-4064-z |
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