Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes

Bibliographic Details
Main Authors: Leslie Bautista, Lucy Pill-Pepe, Neeraj Kapoor, Scott Snyder, Ellen Chu, Paresh Agarwal, Mohammed Sardar, Shylaja Arulkumar, Aym Berges, Mark Iverson, Christopher Behrens, Olivier Marcq, Jeff Fairman
Format: Article
Language:English
Published: American Chemical Society 2022-09-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.2c03481
_version_ 1811181293273088000
author Leslie Bautista
Lucy Pill-Pepe
Neeraj Kapoor
Scott Snyder
Ellen Chu
Paresh Agarwal
Mohammed Sardar
Shylaja Arulkumar
Aym Berges
Mark Iverson
Christopher Behrens
Olivier Marcq
Jeff Fairman
author_facet Leslie Bautista
Lucy Pill-Pepe
Neeraj Kapoor
Scott Snyder
Ellen Chu
Paresh Agarwal
Mohammed Sardar
Shylaja Arulkumar
Aym Berges
Mark Iverson
Christopher Behrens
Olivier Marcq
Jeff Fairman
author_sort Leslie Bautista
collection DOAJ
first_indexed 2024-04-11T09:16:02Z
format Article
id doaj.art-7130dba327a0457f8446578a8ec1f8d8
institution Directory Open Access Journal
issn 2470-1343
language English
last_indexed 2024-04-11T09:16:02Z
publishDate 2022-09-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj.art-7130dba327a0457f8446578a8ec1f8d82022-12-22T04:32:20ZengAmerican Chemical SocietyACS Omega2470-13432022-09-01739349213492810.1021/acsomega.2c03481Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae SerotypesLeslie BautistaLucy Pill-PepeNeeraj KapoorScott SnyderEllen ChuParesh AgarwalMohammed SardarShylaja ArulkumarAym BergesMark IversonChristopher BehrensOlivier MarcqJeff Fairmanhttps://doi.org/10.1021/acsomega.2c03481
spellingShingle Leslie Bautista
Lucy Pill-Pepe
Neeraj Kapoor
Scott Snyder
Ellen Chu
Paresh Agarwal
Mohammed Sardar
Shylaja Arulkumar
Aym Berges
Mark Iverson
Christopher Behrens
Olivier Marcq
Jeff Fairman
Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
ACS Omega
title Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
title_full Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
title_fullStr Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
title_full_unstemmed Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
title_short Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
title_sort addition of lauryldimethylamine n oxide ldao to a copper free click chemistry reaction improves the conjugation efficiency of a cell free generated crm197 variant to clinically important streptococcus pneumoniae serotypes
url https://doi.org/10.1021/acsomega.2c03481
work_keys_str_mv AT lesliebautista additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT lucypillpepe additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT neerajkapoor additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT scottsnyder additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT ellenchu additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT pareshagarwal additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT mohammedsardar additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT shylajaarulkumar additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT aymberges additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT markiverson additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT christopherbehrens additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT oliviermarcq additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes
AT jefffairman additionoflauryldimethylaminenoxideldaotoacopperfreeclickchemistryreactionimprovestheconjugationefficiencyofacellfreegeneratedcrm197varianttoclinicallyimportantstreptococcuspneumoniaeserotypes