An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index
Background and Aims: The prevalence of overweight and obesity consitutes a global epidemic and it is growing around the world. Food and nutrition are essential requirements for promoting health and protecting against non-communicable chronic diseases, such as obesity and cardiovascular disease. Spec...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-06-01
|
| Series: | Frontiers in Nutrition |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnut.2019.00077/full |
| _version_ | 1818578737730420736 |
|---|---|
| author | Yasmin Alaby Martins Ferreira Ana Claudia Pelissari Kravchychyn Sofia de Castro Ferreira Vicente Raquel Munhoz da Silveira Campos Lian Tock Lila Missae Oyama Lila Missae Oyama Valter Tadeu Boldarine Deborah Cristina Landi Masquio David Thivel David Thivel Nitin Shivappa Nitin Shivappa Nitin Shivappa James R. Hébert James R. Hébert James R. Hébert Ana R. Dâmaso |
| author_facet | Yasmin Alaby Martins Ferreira Ana Claudia Pelissari Kravchychyn Sofia de Castro Ferreira Vicente Raquel Munhoz da Silveira Campos Lian Tock Lila Missae Oyama Lila Missae Oyama Valter Tadeu Boldarine Deborah Cristina Landi Masquio David Thivel David Thivel Nitin Shivappa Nitin Shivappa Nitin Shivappa James R. Hébert James R. Hébert James R. Hébert Ana R. Dâmaso |
| author_sort | Yasmin Alaby Martins Ferreira |
| collection | DOAJ |
| description | Background and Aims: The prevalence of overweight and obesity consitutes a global epidemic and it is growing around the world. Food and nutrition are essential requirements for promoting health and protecting against non-communicable chronic diseases, such as obesity and cardiovascular disease. Specific dietary components may modulate inflammation and oxidative stress in obese individuals. The Dietary Inflammatory Index (DII®) was developed to characterize the anti- and pro-inflammatory effects of individuals' diet. Few studies have investigated the role of diet-associated inflammation in adolescents with obesity. The present study aims to investigate the effects of an interdisciplinary weight loss therapy on DII scores and cardiometabolic risk in obese adolescents and possibles correlations.Methods: A total of 45 volunteers (14–19 years old) were recruited and enrolled for long-term interdisciplinary therapy including clinical, nutritional, psychological counseling, and exercise training. Adolescents had access to videos about health education weekly. Body composition and inflammatory and serum profiles were evaluated at baseline and after intervention. The food intake was obtained by 24-h food recall. Data was used to calculate energy-adjusted DII (E-DII) scores. Negative scores indicate an anti-inflammatory diet and positive scores indicates a pro-inflammatory diet. The sample was divided according to whether individuals increased or decreased E-DII scores after therapy.Results: After therapy the body mass index (BMI), body weight, body fat, abdominal, waist, neck, and hip circumferences decreased significantly. The mean of high-density lipoprotein cholesterol (HDL-c) increased after the therapy. There was found an improvement of inflammatory and cardiometabolic parameters. In exploratory analyses, this occurred mainly when the EDII improved.Conclusion: Long-term interdisciplinary therapy combined with a health education website improved inflammatory serum markers in obese adolescents. Reduction in DII scores was associated with reduction of cardiometabolic parameters, suggesting that an anti-inflammatory diet may be an effective strategy to prevent and treat obesity and related comorbidities.Trial:http://www.ensaiosclinicos.gov.br/rg/RBR-6txv3v/, Register Number: RBR-6txv3v |
| first_indexed | 2024-12-16T06:50:34Z |
| format | Article |
| id | doaj.art-7130e67a0e0d4a388d987bc8a2f1a1cd |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-12-16T06:50:34Z |
| publishDate | 2019-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-7130e67a0e0d4a388d987bc8a2f1a1cd2022-12-21T22:40:24ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2019-06-01610.3389/fnut.2019.00077431726An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory IndexYasmin Alaby Martins Ferreira0Ana Claudia Pelissari Kravchychyn1Sofia de Castro Ferreira Vicente2Raquel Munhoz da Silveira Campos3Lian Tock4Lila Missae Oyama5Lila Missae Oyama6Valter Tadeu Boldarine7Deborah Cristina Landi Masquio8David Thivel9David Thivel10Nitin Shivappa11Nitin Shivappa12Nitin Shivappa13James R. Hébert14James R. Hébert15James R. Hébert16Ana R. Dâmaso17Post Graduate Program of Nutrition, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilPost Graduate Program of Nutrition, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilPost Graduate Program of Nutrition, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilTherapeutic Resources Laboratory, Department of Physiotherapy, Universidade Federal de São Carlos (UFSCar), São Carlos, BrazilPost Graduate Program of Nutrition, Universidade Federal de São Paulo, São Paulo, BrazilPost Graduate Program of Nutrition, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilDepartment of Physiology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilDepartment of Physiology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilCentro Universitário São Camilo, São Paulo, BrazilClermont Auvergne University, EA 3533, Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), Clermont-Ferrand, FranceCRNH-Auvergne, Clermont-Ferrand, FranceCancer Prevention and Control Program, University of South Carolina, Columbia, SC, United StatesDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States0Connecting Health Innovations LLC (CHI), Columbia, SC, United StatesCancer Prevention and Control Program, University of South Carolina, Columbia, SC, United StatesDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States0Connecting Health Innovations LLC (CHI), Columbia, SC, United StatesPost Graduate Program of Nutrition, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, BrazilBackground and Aims: The prevalence of overweight and obesity consitutes a global epidemic and it is growing around the world. Food and nutrition are essential requirements for promoting health and protecting against non-communicable chronic diseases, such as obesity and cardiovascular disease. Specific dietary components may modulate inflammation and oxidative stress in obese individuals. The Dietary Inflammatory Index (DII®) was developed to characterize the anti- and pro-inflammatory effects of individuals' diet. Few studies have investigated the role of diet-associated inflammation in adolescents with obesity. The present study aims to investigate the effects of an interdisciplinary weight loss therapy on DII scores and cardiometabolic risk in obese adolescents and possibles correlations.Methods: A total of 45 volunteers (14–19 years old) were recruited and enrolled for long-term interdisciplinary therapy including clinical, nutritional, psychological counseling, and exercise training. Adolescents had access to videos about health education weekly. Body composition and inflammatory and serum profiles were evaluated at baseline and after intervention. The food intake was obtained by 24-h food recall. Data was used to calculate energy-adjusted DII (E-DII) scores. Negative scores indicate an anti-inflammatory diet and positive scores indicates a pro-inflammatory diet. The sample was divided according to whether individuals increased or decreased E-DII scores after therapy.Results: After therapy the body mass index (BMI), body weight, body fat, abdominal, waist, neck, and hip circumferences decreased significantly. The mean of high-density lipoprotein cholesterol (HDL-c) increased after the therapy. There was found an improvement of inflammatory and cardiometabolic parameters. In exploratory analyses, this occurred mainly when the EDII improved.Conclusion: Long-term interdisciplinary therapy combined with a health education website improved inflammatory serum markers in obese adolescents. Reduction in DII scores was associated with reduction of cardiometabolic parameters, suggesting that an anti-inflammatory diet may be an effective strategy to prevent and treat obesity and related comorbidities.Trial:http://www.ensaiosclinicos.gov.br/rg/RBR-6txv3v/, Register Number: RBR-6txv3vhttps://www.frontiersin.org/article/10.3389/fnut.2019.00077/fullinflammatory dietcardiometabolic riskinterdisciplinary therapyobesityinflammation |
| spellingShingle | Yasmin Alaby Martins Ferreira Ana Claudia Pelissari Kravchychyn Sofia de Castro Ferreira Vicente Raquel Munhoz da Silveira Campos Lian Tock Lila Missae Oyama Lila Missae Oyama Valter Tadeu Boldarine Deborah Cristina Landi Masquio David Thivel David Thivel Nitin Shivappa Nitin Shivappa Nitin Shivappa James R. Hébert James R. Hébert James R. Hébert Ana R. Dâmaso An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index Frontiers in Nutrition inflammatory diet cardiometabolic risk interdisciplinary therapy obesity inflammation |
| title | An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index |
| title_full | An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index |
| title_fullStr | An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index |
| title_full_unstemmed | An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index |
| title_short | An Interdisciplinary Weight Loss Program Improves Body Composition and Metabolic Profile in Adolescents With Obesity: Associations With the Dietary Inflammatory Index |
| title_sort | interdisciplinary weight loss program improves body composition and metabolic profile in adolescents with obesity associations with the dietary inflammatory index |
| topic | inflammatory diet cardiometabolic risk interdisciplinary therapy obesity inflammation |
| url | https://www.frontiersin.org/article/10.3389/fnut.2019.00077/full |
| work_keys_str_mv | AT yasminalabymartinsferreira aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT anaclaudiapelissarikravchychyn aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT sofiadecastroferreiravicente aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT raquelmunhozdasilveiracampos aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT liantock aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT lilamissaeoyama aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT lilamissaeoyama aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT valtertadeuboldarine aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT deborahcristinalandimasquio aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT davidthivel aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT davidthivel aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT anardamaso aninterdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT yasminalabymartinsferreira interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT anaclaudiapelissarikravchychyn interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT sofiadecastroferreiravicente interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT raquelmunhozdasilveiracampos interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT liantock interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT lilamissaeoyama interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT lilamissaeoyama interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT valtertadeuboldarine interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT deborahcristinalandimasquio interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT davidthivel interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT davidthivel interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT nitinshivappa interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT jamesrhebert interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex AT anardamaso interdisciplinaryweightlossprogramimprovesbodycompositionandmetabolicprofileinadolescentswithobesityassociationswiththedietaryinflammatoryindex |