INFLUENCE OF SEX DIFFERENCES ON PHARMACOKINETICS OF DRUGS WITHIN THE FRAMEWORK OF BIOEQUIVALENCE STUDIES OF GENERIC MEDICINAL PRODUCTS

Background. Evidence of the effect of sex on the pharmacokinetics of drugs and, accordingly, on the clinical response is significantly accumulated, because of a growing number of clinical studies of the early development of original drugs, which include female subjects. The number of bioequivalence...

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Bibliographic Details
Main Authors: D. P. Romodanovsky, D. V. Goryachev, A. L. Khokhlov, A. E. Miroshnikov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2018-09-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/714

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