The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

Abstract The adaptive immune system and associated inflammation are vital in surveillance and host protection against internal and external threats, but can secondarily damage host tissues. The central nervous system is immune-privileged and largely protected from the circulating inflammatory pathwa...

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Bibliographic Details
Main Authors: Alexa DeMaio, Shikhar Mehrotra, Kumar Sambamurti, Shahid Husain
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Neuroinflammation
Subjects:
T cells
Neurodegeneration
Inflammation
Immune system
Lymphocytes
Online Access:https://doi.org/10.1186/s12974-022-02605-9

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