Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system
Abstract Background Allergic rhinitis includes a certain degree of autonomic imbalance. However, no information is available on how daily changes in allergy burden affect autonomic imbalance. We aimed to estimate associations between daily allergy burden (allergy symptoms and mood) and daily heart r...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
|
| Series: | Clinical and Translational Allergy |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/clt2.12242 |
| _version_ | 1797839118040825856 |
|---|---|
| author | Joren Buekers Michiel Stas Raf Aerts Nicolas Bruffaerts Sebastien Dujardin An VanNieuwenhuyse Jos VanOrshoven Guillaume Chevance Ben Somers Jean‐Marie Aerts Judith Garcia‐Aymerich |
| author_facet | Joren Buekers Michiel Stas Raf Aerts Nicolas Bruffaerts Sebastien Dujardin An VanNieuwenhuyse Jos VanOrshoven Guillaume Chevance Ben Somers Jean‐Marie Aerts Judith Garcia‐Aymerich |
| author_sort | Joren Buekers |
| collection | DOAJ |
| description | Abstract Background Allergic rhinitis includes a certain degree of autonomic imbalance. However, no information is available on how daily changes in allergy burden affect autonomic imbalance. We aimed to estimate associations between daily allergy burden (allergy symptoms and mood) and daily heart rate characteristics (resting heart rate and sample entropy, both biomarkers of autonomic balance) of adults with allergic rhinitis, based on real‐world measurements with a wearable telemonitoring system. Methods Adults with a tree pollen allergy used a smartphone application to self‐report daily allergy symptoms (score 0–44) and mood (score 0–4), and a Mio Alpha 2 wristwatch to collect heart rate characteristics during two pollen seasons of hazel, alder and birch in Belgium. Associations between daily allergy burden and heart rate characteristics were estimated using linear mixed effects distributed lag models with a random intercept for individuals and adjusted for potential confounders. Results Analyses included 2497 participant‐days of 72 participants. A one‐point increase in allergy symptom score was associated with an increase in next‐day resting heart rate of 0.08 (95% CI: 0.02–0.15) beats per minute. A one‐point increase in mood score was associated with an increase in same‐day sample entropy of 0.80 (95% CI: 0.34–1.26) × 10−2. No associations were found between allergy symptoms and heart rate sample entropy, nor between mood and resting heart rate. Conclusion Daily repeated measurements with a wearable telemonitoring system revealed that the daily allergy burden of adults with allergic rhinitis has systemic effects beyond merely the respiratory system. |
| first_indexed | 2024-04-09T15:53:03Z |
| format | Article |
| id | doaj.art-71350982e3ab4cea942b2e51166574a7 |
| institution | Directory Open Access Journal |
| issn | 2045-7022 |
| language | English |
| last_indexed | 2024-04-09T15:53:03Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Allergy |
| spelling | doaj.art-71350982e3ab4cea942b2e51166574a72023-04-26T04:54:37ZengWileyClinical and Translational Allergy2045-70222023-04-01134n/an/a10.1002/clt2.12242Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring systemJoren Buekers0Michiel Stas1Raf Aerts2Nicolas Bruffaerts3Sebastien Dujardin4An VanNieuwenhuyse5Jos VanOrshoven6Guillaume Chevance7Ben Somers8Jean‐Marie Aerts9Judith Garcia‐Aymerich10ISGlobal Barcelona SpainMeasure, Model & Manage Bioresponses (M3‐BIORES) Department of Biosystems KU Leuven Leuven BelgiumRisk and Health Impact Assessment Sciensano (Belgian Institute of Health) Brussels BelgiumMycology and Aerobiology Sciensano (Belgian Institute of Health) Brussels BelgiumDepartment of Geography University of Namur Namur BelgiumCentre of Environment and Health Department of Public Health and Primary Care KU Leuven Leuven BelgiumDivision of Forest, Nature and Landscape Department of Earth and Environmental Sciences KU Leuven Leuven BelgiumISGlobal Barcelona SpainDivision of Forest, Nature and Landscape Department of Earth and Environmental Sciences KU Leuven Leuven BelgiumMeasure, Model & Manage Bioresponses (M3‐BIORES) Department of Biosystems KU Leuven Leuven BelgiumISGlobal Barcelona SpainAbstract Background Allergic rhinitis includes a certain degree of autonomic imbalance. However, no information is available on how daily changes in allergy burden affect autonomic imbalance. We aimed to estimate associations between daily allergy burden (allergy symptoms and mood) and daily heart rate characteristics (resting heart rate and sample entropy, both biomarkers of autonomic balance) of adults with allergic rhinitis, based on real‐world measurements with a wearable telemonitoring system. Methods Adults with a tree pollen allergy used a smartphone application to self‐report daily allergy symptoms (score 0–44) and mood (score 0–4), and a Mio Alpha 2 wristwatch to collect heart rate characteristics during two pollen seasons of hazel, alder and birch in Belgium. Associations between daily allergy burden and heart rate characteristics were estimated using linear mixed effects distributed lag models with a random intercept for individuals and adjusted for potential confounders. Results Analyses included 2497 participant‐days of 72 participants. A one‐point increase in allergy symptom score was associated with an increase in next‐day resting heart rate of 0.08 (95% CI: 0.02–0.15) beats per minute. A one‐point increase in mood score was associated with an increase in same‐day sample entropy of 0.80 (95% CI: 0.34–1.26) × 10−2. No associations were found between allergy symptoms and heart rate sample entropy, nor between mood and resting heart rate. Conclusion Daily repeated measurements with a wearable telemonitoring system revealed that the daily allergy burden of adults with allergic rhinitis has systemic effects beyond merely the respiratory system.https://doi.org/10.1002/clt2.12242allergic rhinitisheart ratesmartphonesymptomstelemonitoring |
| spellingShingle | Joren Buekers Michiel Stas Raf Aerts Nicolas Bruffaerts Sebastien Dujardin An VanNieuwenhuyse Jos VanOrshoven Guillaume Chevance Ben Somers Jean‐Marie Aerts Judith Garcia‐Aymerich Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system Clinical and Translational Allergy allergic rhinitis heart rate smartphone symptoms telemonitoring |
| title | Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| title_full | Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| title_fullStr | Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| title_full_unstemmed | Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| title_short | Daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| title_sort | daily allergy burden and heart rate characteristics in adults with allergic rhinitis based on a wearable telemonitoring system |
| topic | allergic rhinitis heart rate smartphone symptoms telemonitoring |
| url | https://doi.org/10.1002/clt2.12242 |
| work_keys_str_mv | AT jorenbuekers dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT michielstas dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT rafaerts dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT nicolasbruffaerts dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT sebastiendujardin dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT anvannieuwenhuyse dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT josvanorshoven dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT guillaumechevance dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT bensomers dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT jeanmarieaerts dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem AT judithgarciaaymerich dailyallergyburdenandheartratecharacteristicsinadultswithallergicrhinitisbasedonawearabletelemonitoringsystem |