Cationic Vitamin E-TPGS Mixed Micelles of Berberine to Neutralize Doxorubicin-Induced Cardiotoxicity via Amelioration of Mitochondrial Dysfunction and Impeding Apoptosis

Cationic Vitamin E-TPGS Mixed Micelles of Berberine to Neutralize Doxorubicin-Induced Cardiotoxicity via Amelioration of Mitochondrial Dysfunction and Impeding Apoptosis

Anthracycline antibiotics, namely, doxorubicin (DOX) and daunorubicin, are among the most widely used anticancer therapies, yet are notoriously associated with severe myocardial damage due to oxidative stress and mitochondrial damage. Studies have indicated the strong pharmacological properties of B...

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Bibliographic Details
Main Authors: Abdelkader A. Metwally, Samayita Ganguly, Nora Biomi, Mingyi Yao, Tamer Elbayoumi
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
anthracycline antibiotics
doxorubicin
cardiomyopathy
apoptosis
berberine
mitohormetic
Online Access:https://www.mdpi.com/1420-3049/29/5/1155

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